Smoking during pregnancy may not cause ADHD in children after all – Innovita Research

Smoking during pregnancy may not cause ADHD in children after all

A new systematic review and meta-analysis published in the scientific journal Addiction and led by University of Bristol researchers show that maternal prenatal smoking is associated with offspring attention-deficit hyperactivity disorder (ADHD) but is unlikely to be its cause.

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Several studies have indicated that maternal smoking during pregnancy may contribute to offspring ADHD; however, it is unclear whether this reflects an actual causal effect or is the result of confounding factors such as socioeconomic position, education, income and maternal age.  This new review attempted to find an answer to that question.

The review looked at 46 prior studies that assessed the association between maternal prenatal smoking and offspring ADHD diagnosis.  The review specifically included studies accounting for genetic effects and conventional approaches.

Some of those studies had a low risk of bias (meaning they are unlikely to give misleading results) and were able to take into account genetic effects.  Those studies indicate that shared genetics plays a substantial role in associating offspring ADHD with prenatal smoking. This is supported by a previous systematic review based on genetically informed designs which also concluded that the association between maternal prenatal smoking and ADHD is explained by shared genetics. 

Lead author Dr Elis Haan, an Honorary Research Associate at Bristol’s School of Psychological Science, says, “Our systematic review shows no causal effect between maternal prenatal smoking and offspring ADHD diagnosis. However, pregnant women should still be advised not to smoke during pregnancy, as prenatal smoking has harmful effects on other child health outcomes.”

Source: University of Bristol