General – Innovita Research
March 20, 2019

Mutations in noncoding genes could play big role in regulating cancer, study finds

RNA transcribed from genes that seem not to code for anything may play an important role in regulating cancer, a new study suggests. A number of these noncoding RNA fragments lie next to known cancer genes, the study found. Understanding how they interact with those cancer genes could open new […]
March 20, 2019

Study: Free fatty acids appear to rewire cells to promote obesity-related breast cancer

Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women’s elevated risk of developing breast cancer after menopause. “When taken up by estrogen-receptor positive breast cancer cells, these […]
March 20, 2019

Narcolepsy may be caused by the body attacking itself

Researchers from DTU and the University of Copenhagen are now pointing out that narcolepsy is an autoimmune disease. This may be important to future treatment of this chronic disorder. Between 2,500 and 3,000 Danes suffer from the sleep disorder narcolepsy—which is characterized by a sudden and overwhelming urge to sleep. […]
March 20, 2019

UW team finds key to common cancer pathway in discovery that could unlock new therapies

Scientists have long known that the protein p53, when mutated, is a critical factor in the onset of many different kinds of cancer. In its unmutated form, however, it is known to protect against cancer. These dueling qualities make the p53 protein and the gene that makes it among the […]
March 20, 2019

Speed limit on DNA-making sets pace for life’s first steps

Scientists puzzled for two decades over this seemingly unnecessary withholding. Now researchers at Princeton University have shown that the inhibiting mechanism, controlled by an enzyme known as RNR, is key to the embryo’s survival. Too much material early on leads to disaster for the fledgling lifeform. “This study shows us […]
March 20, 2019

Grow a better jawbone in your ribs

The jawbone is not typically connected to the rib bone, but it might be in an emergency. Rice University bioengineers and their colleagues have developed a technique to grow live bone to repair craniofacial injuries by attaching a 3D-printed bioreactor — basically, a mold — to a rib. Stem cells and blood vessels from […]
March 20, 2019

With single gene insertion, blind mice regain sight

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems. They were able to see motion, brightness changes over a thousandfold […]
March 20, 2019

Light physical activity linked to lower risk of heart disease in older women

Light physical activity such as gardening, strolling through a park, and folding clothes might be enough to significantly lower the risk of cardiovascular disease among women 63 and older, a new study has found. This kind of activity, researchers said, appears to reduce the risk of cardiovascular disease events such […]
March 19, 2019

Researchers from Cambridge Grow a ‘Mini-Brain’ Capable of Contracting Muscle

A group of researchers from the University of Cambridge have grown a miniature (roughly pea-sized) brain in a dish which they claim might “improve our understanding of human brain development and neurological disorders”. The paper accompanying the work, published in the journal Nature Neuroscience, details how a grey blob of […]
March 19, 2019

Surgery no better than medication at preventing serious complications of atrial fibrillation

Catheter ablation, a common cardiovascular procedure, appears no more effective than drug therapies in preventing strokes, deaths, and other complications in patients with atrial fibrillation. However, patients who get the procedure experience much greater symptom relief and long-term improvements in the quality of life, including  fewer recurrences of the condition […]
March 19, 2019

Colorectal Cancer Screening Might Need to Start Sooner Than You Thought

Thinking you could wait till your 50th birthday to worry about colorectal cancer? Maybe not. New guidelines from the American Cancer Society recognize recent studies that have found increasing rates of colorectal cancer among younger people. In response, they lowered the recommended age to begin screening from 50 to 45. “Research […]
March 19, 2019

Chronic Short Sleep Associated With Adolescent Obesity

Older children and teenagers may have a higher risk of obesity if they consistently don’t get enough sleep, according to recent Michigan Medicine research. The study, published in the Journal of Pediatrics, found the highest levels of obesity in adolescents who weren’t sleeping enough night after night, even more so than […]
March 19, 2019

Researchers find the immune system's unknown messenger

Researchers can now explain how a cell that is being attacked by bacteria or viruses specifically manages to ‘sound the alarm’ among its neighbouring cells so they can react with a quick response. “We’ve succeeded in finding and describing a messenger which both quickly and effectively can inform the surrounding […]
March 19, 2019

Chromatin changes rapidly in response to low oxygen, study finds

Research by Professor Sonia Rocha and her team at the Institute of Integrative Biology reveals new insights into how cells respond to oxygen deprivation. Published in the prestigious journal Science, the researchers found that chromatin, the complex of DNA and proteins where all genes reside, quickly changes in response to low oxygen. Oxygen is essential for […]
March 19, 2019

A new approach to drugging a difficult cancer target

One of the most common cancer-promoting genes, known as Myc, is also one of the most difficult to target with drugs. Scientists have long tried to develop drugs that block the Myc protein, but so far their efforts have not been successful. Now, using an alternative strategy, MIT researchers have […]
March 19, 2019

Brain wave stimulation may improve Alzheimer’s symptoms

By exposing mice to a unique combination of light and sound, MIT neuroscientists have shown that they can improve cognitive and memory impairments similar to those seen in Alzheimer’s patients. This noninvasive treatment, which works by inducing brain waves known as gamma oscillations, also greatly reduced the number of amyloid […]
March 18, 2019

Preclinical Data Shows Combination Immunotherapy Could Stop Liver Cancer Growth

Even as overall cancer incidence and mortality decrease in the United States, the number of people diagnosed with liver cancer is on the rise. Current therapies for liver cancer are largely ineffective, resulting in poor outcomes, but new preclinical data from University of California San Diego School of Medicine offers […]
March 18, 2019

UC San Diego Study Points to Virus-Related Acceleration in Some Cancers

While the human T- cell leukemia virus type 1 (HTLV-1) is known to cause a rare cancer of the immune system’s T-cells called adult T-cell leukemia or ATL in about five percent of those infected, researchers from the San Diego Supercomputer Center (SDSC) and Moores Cancer Center at UC San […]
March 18, 2019

Study recommends new ways to treat musculoskeletal pain

A new study led by The University of Western Australia has identified 11 recommendations to help health professionals and patients better manage musculoskeletal problems. The study comes after the team found many musculoskeletal problems were not being managed effectively. Musculoskeletal conditions – including back and neck pain, osteoarthritis and shoulder […]
March 18, 2019

Treating heart failure at home

Heart failure – a condition in which the heart muscle can no longer pump enough blood to meet the body’s needs, and distinct from a heart attack – is the most common reason Americans age 65 and older are hospitalized. And while we spend nearly $31 billion annually dealing with […]
March 18, 2019

Skin Repair Eliminates ‘Inflamm-Aging’ Linked to Chronic Disease

Skin is the body’s largest organ, and scientists at UC San Francisco and the San Francisco Veterans Administration (VA) Health Care System think it may be to blame for body-wide inflammation linked to numerous chronic diseases of aging. The good news is that properly caring for the skin with a moisturizing cream […]
March 18, 2019

SPIT lab leading the effort to analyze hair, expand research on puberty

Puberty is something we all go through and yet there is limited science to explain what is happening inside our bodies during this transition, and how it affects our physical and mental health. The research that does exist focuses primarily on girls and often ignores the changes for boys, African […]
March 18, 2019

Therapy could improve, prolong sight in those suffering vision loss

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness. The treatment — involving either a drug or gene therapy — works by reducing […]
March 17, 2019

Didn't get enough sleep again? 4 ways sleep deprivation damages your body and your mind

You know you should always sleep for 7-8 hours. You can feel when your body didn‘t get enough sleep. And yet sometimes you just cannot go to bed on time and end up sleeping less than ideal. But do you know what happens to your body and mind because of […]
March 15, 2019

Your healthy food is not going to protect you from dementia

Having a good healthy diet is extremely important and everyone knows that. You should eat enough fruits and vegetables, while at the same time restrain yourself from eating too many sweets and junk food. However, sometimes there are certain myths about a healthy diet. Scientists from UCL say that the […]
March 15, 2019

UNH Researchers Create a Hydrogel Contact Lens to Treat Serious Eye Disease

Researchers at the University of New Hampshire have created a hydrogel that could one day be made into a contact lens to more effectively treat corneal melting, a condition that is a significant cause for blindness world-wide. The incurable eye disease can be initiated by a number of different causes such […]
March 15, 2019

UC awarded third CRISPR patent, expanding its gene-editing portfolio

The University of California announced today that the U.S. Patent and Trademark Office (USPTO) issued U.S. Patent Number 10,227,611 covering use of single-molecule RNA guides and Cas9 protein in any cell, thus creating efficient and effective ways for scientists to target and edit genes. This patent is co-owned by The […]
March 15, 2019

Biosensor may provide better cancer diagnosis

Lawrence Livermore National Laboratory (LLNL) researchers have developed a new biological sensor that could help clinicians better diagnose cancer and epilepsy. Biological sensors monitor small molecules, ions and protons and are vital as a medical diagnostic. Even the simplest signals, such as intracellular pH level, can provide important information for […]
March 15, 2019

Researchers explore link between metal exposure and Parkinson’s symptoms

A new study from Iowa State University biomedical researchers illuminates the biological processes by which exposure to some metals can contribute to the onset of Parkinson’s-like symptoms. The study, published in the peer-reviewed journal Science Signaling, focuses on the metal manganese, which has a range of industrial uses as an alloy. […]
March 15, 2019

Poor sleep a problem for foster children

Children living in foster care may have a higher risk of developing insomnia, and this can lead to long-term mental and physical health problems, according to a study led by researchers at the University of Georgia. The researchers conducted in-depth interviews with 24 adults who lived in foster care to learn […]