General – Page 200 – Innovita Research
January 3, 2020

When you eat might be as important as what you eat

During the years 1976 through 1980, 15% of U.S. adults were obese. Today, about 40% of adults are obese. Another 33% are overweight. Coinciding with this increase in weight are ever-rising rates of heart disease, diabetes, cancer and health complications caused by obesity, such as hypertension. Even Alzheimer’s disease may […]
January 3, 2020

Versatile bile acids

Could bile acids—the fat-dissolving juices churned out by the liver and gallbladder—also play a role in immunity and inflammation? The answer appears to be yes, according to two separate Harvard Medical School studies published in Nature. The findings of the two studies, both conducted in mice, show that bile acids promote […]
January 3, 2020

Redefining Sexual Identity with Parkinson’s Disease

Discussions about sexual health can be awkward, but for Daniela Wittmann, Ph.D., MSW, they go with the territory. As a social certified sex therapist, she sees patients with sexual health issues at the Michigan Medicine Center for Sexual Health and in the Department of Urology. She also discusses these types of issues with Parkinson’s disease patients during […]
January 2, 2020

Closer to identifying leukemic stem cells

Acute myeloid leukaemia is the most common type of leukaemia in adults. It is characterized by the pathological expansion of immature cells (myeloblasts) that invade the bone marrow and expand into the blood, affecting the production of the rest of the healthy cells. Although patients usually respond well to chemotherapy-based […]
January 2, 2020

New treatment for heart attack scar could address heart failure

Heart disease remains the largest killer in Australia and around the world. A new study has shown that a protein therapy– recombinant human platelet-derived growth factor-AB (rhPDGF-AB) – could improve outcomes following heart attack. After a heart attack, scar tissue forms and this negatively affects heart function. Now, researchers from […]
January 2, 2020

Short or long sleep associated with Pulmonary Fibrosis

Scientists have discovered that people who regularly sleep for more than 11 hours or less than 4 hours are 2-3 times more likely to have the incurable disease, pulmonary fibrosis, compared to those that sleep for 7 hours in a day. They attribute this association to the body clock. The […]
January 2, 2020

Alzheimer ‘Tau’ Protein Far Surpasses Amyloid in Predicting Toll on Brain Tissue

Brain imaging of pathological tau-protein “tangles” reliably predict the location of future brain atrophy in Alzheimer’s patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid “plaques,” which have been the […]
December 31, 2019

Developmental changes in the brain may influence how often adolescents get drunk

A new study led by researchers at King’s College London has found that adolescents with particular patterns of brain development report an increased frequency in drunkenness. The research was published in JAMA Psychiatry. Using brain imaging data collected from 726 healthy adolescents, the researchers analysed changes in the volume of […]
December 31, 2019

Study finds potential link between cardiovascular death and some types of pesticides

A new study from the University of Iowa suggests that people who have higher levels of a chemical in their body that indicates exposure to commonly used insecticides die of cardiovascular disease at a significantly higher rate. Findings from the study, published in the journal JAMA Internal Medicine, suggest those who have […]
December 31, 2019

Vitamin D increases protection against infection, new model suggests

Oregon State University researchers have led the development of a new model for studying vitamin D’s role in infection prevention, and tests using the model suggest that vitamin D treatment can dramatically reduce the number of disease-causing bacteria in skin wounds. In addition to shedding light on infection-prevention potential, the […]
December 31, 2019

Body Temperature May Provide Early Warning for Graft-Versus-Host Disease, a Study in Mice Suggests

Proof-of-concept research points to wearable monitors’ potential to offer low-cost, non-invasive way to detect this dangerous bone-marrow transplant complication. By continuously monitoring the body temperature of mice that had undergone bone-marrow transplants, researchers were able to detect early warning signs of graft-versus-host disease — a dangerous, sometimes deadly response of […]
December 30, 2019

Caffeine may offset some health risks of diets high in fat, sugar

A new study in rats suggests that caffeine may offset some of the negative effects of an obesogenic diet by reducing the storage of lipids in fat cells and limiting weight gain and the production of triglycerides. Rats that consumed the caffeine extracted from mate tea gained 16% less weight […]
December 30, 2019

Microbes are at work in our bodies, and researchers have figured out what they're up to

An algorithm akin to the annoyingly helpful one that attempts to auto-complete text messages and emails is now being harnessed for a better cause. NSF-funded researchers at Drexel University are using its pattern-recognition ability to identify microbial communities in the human body by sifting through volumes of genetic code. Their method could speed the […]
December 27, 2019

Finally, machine learning interprets gene regulation clearly

In this age of “big data,” artificial intelligence (AI) has become a valuable ally for scientists. Machine learning algorithms, for instance, are helping biologists make sense of the dizzying number of molecular signals that control how genes function. But as new algorithms are developed to analyze even more data, they […]
December 27, 2019

Calcium channels play a key role in the development of diabetes

Researchers at Karolinska Institutet in Sweden have deciphered the diabetogenic role of a certain type of calcium channel in insulin-secreting beta cells. The researchers believe that blockade of these channels could be a potential new treatment strategy for diabetes. The study is published in the scientific journal PNAS. CaV3.1 channels […]
December 27, 2019

Clinical trials planned for brain tumor ‘GPS’ maps

A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in pinpointing brain tumors and will soon be tested in real-time with patients at Cleveland Clinic under a three-year, $600,000 V Foundation grant. The grant was awarded to Pallavi Tiwari, […]
December 27, 2019

Why isn’t there a vaccine for staph?

Staph bacteria, the leading cause of potentially dangerous skin infections, are most feared for the drug-resistant strains that have become a serious threat to public health. Attempts to develop a vaccine against methicillin-resistant Staphylococcus aureus (MRSA) have failed to outsmart the superbug’s ubiquity and adaptability to antibiotics. Now, a study from Washington […]
December 27, 2019

A New Era is Dawning in Cystic Fibrosis Treatment

As her health began to worsen in late 2017, Annette Quinn started measuring her declining lung function by making note of the number of days between episodes of hemoptysis or coughing up blood. At first, the episodes occurred once every few months. But by the summer of 2018, Quinn experienced […]
December 27, 2019

Penn Researchers Predict 10-Year Breast Cancer Recurrence with MRI Scans

Diverse diseases like breast cancer can present challenges for clinicians, specifically on a cellular level. While one patient’s tumor may differ from another’s, the cells within the tumor of a single patient can also vary greatly. This can be problematic, considering that an examination of a tumor usually relies on a biopsy, which […]
December 27, 2019

Mindfulness video game changes areas of the brain associated with attention

With an estimated 97 percent of adolescents playing video games in their free time, there is growing potential to design games as tools for attention-building instead of attention-busting. A research team at the Center for Healthy Minds at the University of Wisconsin–Madison and the University of California, Irvine, designed a video game […]
December 27, 2019

Researchers Solve Protein Structure Associated with Inherited Retinal Diseases

Researchers at the University of New Hampshire have reported the first structural model for a key enzyme, and its activating protein, that can play a role in some genetically inherited eye diseases like retinitis pigmentosa and night blindness. “There has been substantial research on the biochemical pathway involving this enzyme, […]
December 26, 2019

New method gives hope in understanding Alzheimer’s disease

Scientists are now able to label proteins in the brains of living mice who have a disease similar to Alzheimer’s disease, and have the labels remain in place. The tracer molecules have been developed at Linköping University. The new method allows the researchers to observe how harmful protein aggregates form […]
December 26, 2019

Sysmex Presents Academic Report with a View to Creating a Simple Method of Diagnosing Alzheimer's Disease Using Blood

Sysmex Corporation and Eisai Co., Ltd. are pursuing a joint project to develop a method of diagnosing Alzheimer's disease (AD) using blood, presented two posters showing the most recent data from the project. The presentations took place at the 12th Clinical Trials on Alzheimer's Disease (CTAD) conference, from December 4 […]
December 24, 2019

Motor neurone disease linked to cholesterol imbalance in cells

Scientists have developed a new theory on the underlying cause of motor neurone disease, which could lead to more accurate diagnosis for patients and new treatments. A team at the University of Exeter has found evidence that the condition is caused by an imbalance in cholesterol and other fat levels […]
December 24, 2019

For CRISPR, tweaking DNA fragments before inserting yields highest efficiency rates yet

University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications. By chemically tweaking the ends of the DNA to be inserted, the new technique is up to five times more […]
December 24, 2019

Measuring Mutations in Sperm May Reveal Risk for Autism in Future Children

Spontaneous mutations in paternal sperm are linked to autism spectrum disorder; researchers have developed way to quantify those mutations and assess chances the mutations will cause disease. The causes of autism spectrum disorder or ASD are not fully understood; researchers believe both genetics and environment play a role. In some […]