General – Page 111 – Innovita Research
June 28, 2021

New approach to treat inflammatory disorders while preserving protection against opportunistic infections

Researchers at Case Western Reserve University have discovered a new technique to control inflammatory disorders that also maintains a patient’s ability to fight off infections. Principal investigator Carlos Subauste, professor of medicine and pathology at the Case Western Reserve School of Medicine, and his team have identified the interaction of […]
June 28, 2021

Switching to 80% ULTRA-processed food diet for 30 days: What would happen?

Eating healthy is not easy. This is especially true today, when all the supermarkets are full of ready-made, ready-to-eat kinds of food. It is no wonder why many people choose such products on a daily basis: these ultra-processed meals are produced to taste good, are relatively inexpensive, and do not […]
June 27, 2021

Study identifies heart block cause in athletes

An international team of scientists from Manchester, Montpellier and Copenhagen have identified why some endurance athletes experience a heart rhythm disturbance called ‘heart block’. The University of Manchester-led study found that long-term exercise in retired racehorses – the best available model of the athlete’s heart – and in mice, triggered […]
June 27, 2021

As novel sights become familiar, different brain rhythms and neurons take over

As “visual recognition memory” emerges in the visual cortex, one circuit of inhibitory neurons supplants another, and slower neural oscillations prevail. To focus on what’s new, we disregard what’s not. A new study by researchers at MIT’s Picower Institute for Learning and Memory substantially advances understanding of how a mammalian […]
June 27, 2021

AI breakthrough in premature baby care

James Cook University scientists believe they have made a breakthrough in the science of keeping premature babies alive. As part of her PhD work, JCU engineering lecturer Stephanie Baker led a pilot study that used a hybrid neural network to accurately predict how much risk individual premature babies face. She […]
June 27, 2021

Soil microbes metabolize the same polyphenols found in chocolate, wine

Fruits, vegetables, red wine and chocolate are all rich in polyphenols, plant compounds that double as cancer-fighting antioxidants. Humans can access these foods' health benefits because the microbes in our guts happily feast on them, breaking them down into smaller chemical components. Microbiome scientists at Colorado State University wanted to know if […]
June 26, 2021

Platinum-chemotherapy can enhance the treatment resistance of ovarian cancer cells

Researchers from Karolinska Institutet have discovered how platinum-chemotherapy can enhance the treatment resistance of ovarian cancer cells, by progressively changing the cancer cell-intrinsic adhesion signalling and cell-surrounding microenvironment. Platinum chemotherapy is a standard treatment in ovarian cancers, but treatment resistance commonly develops. The extracellular matrix (ECM)-derived biochemical and mechanical cues […]
June 26, 2021

Immune cells in the human biliary system mapped

Researchers at Karolinska Institutet have analysed and described in detail the immune cells residing in the human bile duct. The findings may pave the way for new treatment strategies against disorders of the bile duct, which are often linked to immunological processes. The study is published in the journal Science […]
June 26, 2021

Hope for children with high-risk neuroblastoma

Thanks to many years of translational research, some children with the rare childhood cancer neuroblastoma may now be cured. In a study published in the Journal of Clinical Oncology, researchers at among others Karolinska Institutet and the University of Gothenburg write that a so-called ALK inhibitor should be tried to […]
June 26, 2021

Seeking a treatment for IBS pain in tarantula venom

For patients who have inflammatory bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic — or long-term — abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study in ACS Pharmacology & Translational Science, researchers identify a […]
June 26, 2021

Blood test shows promise for predicting treatment response in metastatic HPV-positive throat cancer

A sensitive blood test being developed by a team of researchers at the University of Michigan Rogel Cancer Center shows promise for predicting whether patients with metastatic HPV-positive throat cancer will respond to treatment months earlier than standard imaging scans. That’s according to a study, published in Oncotarget, validating the test in a small group of patients […]
June 25, 2021

Novel Risk Score for Predicting Blood Cancer Relapse

Medical researchers in China develop a new risk score to predict relapse of leukemia. Several patients suffering from leukemia, who have undergone stem cell transplantation, are at a risk of relapse, owing to varied reasons. Before the inevitable, what if it is possible to predict this situation, and take appropriate […]
June 25, 2021

Predicting Tooth Loss

Tooth loss is often accepted as a natural part of ageing, but what if there was a way to better identify those most susceptible without the need for a dental exam? New research led by investigators at Harvard School of Dental Medicine suggests that machine learning tools can help identify […]
June 25, 2021

NIH scientists describe “multi-kingdom dialogue” between internal, external microbiota

National Institutes of Health scientists and their collaborators have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as obesity and inflammatory skin disorders develop. The new research is published in Cell. The billions of organisms living on body […]
June 25, 2021

Study suggests scientists may need to rethink which genes control aging

To better understand the role of bacteria in health and disease, National Institutes of Health researchers fed fruit flies antibiotics and monitored the lifetime activity of hundreds of genes that scientists have traditionally thought control aging. To their surprise, the antibiotics not only extended the lives of the flies but […]
June 25, 2021

New snack foods nurture healthy gut microbiome

Researchers at Washington University School of Medicine in St. Louis have identified ingredients for snack food prototypes that have been formulated to deliberately change the gut microbiome in ways that can be linked to health. Translating results from animal models, the scientists have shown in two pilot human studies of […]
June 25, 2021

Virus that causes COVID-19 can find alternate route to infect cells

Early in the COVID-19 pandemic, scientists identified how SARS-CoV-2, the virus that causes COVID-19, gets inside cells to cause infection. All current COVID-19 vaccines and antibody-based therapeutics were designed to disrupt this route into cells, which requires a receptor called ACE2. Now, researchers at Washington University School of Medicine in […]
June 25, 2021

With remarkable similarities to MS, a disease in dogs opens new avenues for study

The canine disease granulomatous meningoencephalomyelitis (GME), the most common neuroinflammatory disease that affects dogs, shares key features of its pathology and immunology with multiple sclerosis (MS), according to a new study. A detailed investigation of GME by a team led by Molly Church and Jorge Iván Alvarez of Penn’s School of Veterinary Medicine, incorporating MRI […]
June 25, 2021

How mRNA Vaccines Help Fight Cancer Tumors, Too

Thanks to researchers in different fields who put in nearly two decades of past work on mRNA vaccine technology, people around the world are being immunized today from COVID-19 — and hopefully leading us out of this pandemic. Now, because of the increased focus on this versatile technology and that foundation […]
June 25, 2021

Bourneville's tuberous sclerosis: everything unfolds in the brain shortly after birth

A Canadian research team has uncovered a new mechanism involved in Bourneville tuberous sclerosis (BTS), a genetic disease of childhood. The team hypothesizes that a mutation in the TSC1 gene causes neurodevelopmental disorders that develop in conjunction with the disease. Seen in one in 6,000 children, tuberous sclerosis causes benign […]
June 25, 2021

Drug doubles down on bone cancer, metastasis

Bone cancer is hard to treat and prone to metastasis. Research teams at Rice University and Baylor College of Medicine have a new strategy to attack it. Chemist Han Xiao at Rice and biologist Xiang Zhang at Baylor and their labs have developed an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits […]
June 24, 2021

Finding the love hormone in a stressed-out world

A new art/science collaboration uses molecular structures as its creative medium. In Jenna Sutela’s work, which ranges from computational poetry to experimental music to installations and performance, the MIT Center for Art, Science & Technology (CAST) Visiting Artist enlists microbes and neural networks as co-creators. “I want to explore this notion […]
June 24, 2021

Uncovering the mysteries of milk

PhD student Sarah Nyquist applies computational methods to understudied areas of reproductive health, such as the cellular composition of breast milk. Sarah Nyquist got her first introduction to biology during high school, when she took an online MIT course taught by genomics pioneer Eric Lander. Initially unsure what to expect, […]
June 24, 2021

Exploring links between segregation and cardiovascular diseases

A University of Texas at Arlington researcher is examining how historic segregation in the United States may contribute to cardiovascular disease among individuals from minority or low-income groups. “If this research does find neighborhood factors, like racial segregation and income, impact cardiovascular disease in minority and low-income people, then we […]
June 23, 2021

Scientists designed a promising non-invasive treatment for Alzheimer’s disease

Blood-brain barrier typically protects the brain, but is also quite a bit of a challenge for scientists trying to create therapies for neurological conditions. Drugs that should act on the brain struggle to pass this barrier. Now scientists at The University of Queensland have found that an ultrasound therapy could […]
June 23, 2021

Latest data on immune response to COVID-19 reinforces need for vaccination

New research has found that previous infection, whether it was symptomatic or asymptomatic, does not necessarily protect you long-term from COVID-19, particularly against new Variants of Concern. The preprint study was led by the University of Oxford, in collaboration with the Universities of Liverpool, Sheffield, Newcastle and Birmingham with support […]