General – Page 272 – Innovita Research
September 10, 2018

Chronic Diseases Driven by Metabolic Dysfunction

Much of modern Western medicine is based upon the treatment of acute, immediate harm, from physical injury to infections, from broken bones and the common cold to heart and asthma attacks. But progress in treating chronic illness, where the cause of the problem is often unknown—and, in fact, may no […]
September 7, 2018

Changes in the architecture around cancer cells can fuel their spread

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption. The study shows that acute changes in a single component of the extracellular matrix can trigger a very […]
September 7, 2018

Diseased heart muscle cells have abnormally shortened telomeres

People with a form of heart disease called cardiomyopathy have abnormally short telomeres in heart muscle cells responsible for contraction, according to a new study by researchers at the Stanford University School of Medicine. A telomere is a DNA sequence that serves as a protective cap on the ends of chromosomes. […]
September 7, 2018

Focused delivery for brain cancers

A person’s brainstem controls some of the body’s most important functions, including heart beat, respiration, blood pressure and swallowing. Tumor growth in this part of the brain is therefore twice as devastating. Not only can such a growth disrupt vital functions, but operating in this area is so risky, many […]
September 7, 2018

New clues found to understanding relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington University School of Medicine in St. Louis, the Baylor College of Medicine and the University of […]
September 7, 2018

Scientists identify weak point in deadly eye melanoma

A natural plant compound exploits a newly identified Achilles’ heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. […]
September 7, 2018

Scientists develop new way to identify breast cancer tumors

research team led by USC scientists has developed a new way to identify molecular markers of breast cancer tumors, a potentially lifesaving breakthrough that could lead to better treatment for millions of women. Aided by machine learning, the researchers taught a computer to rapidly sort images of breast tumors to […]
September 7, 2018

Scientists discover new function of heat-shock protein

New research by teams at UNSW and VIB-KU Leuven in Belgium shows that that in addition to its well-known role as a protein chaperone, heat-shock protein Hsp90 also stimulates exosome release. The findings – published in academic journal Molecular Cell – shed new light on treatment strategies for both cancer and neurodegenerative […]
September 6, 2018

Aging Connection

For decades researchers have worked to shed light on the causes of neurodegenerative disorders, a group of devastating conditions, including Alzheimer’s and Parkinson’s, that involve the progressive loss of neurons and nervous system function. In recent years, numerous factors, from genetic mutations to viral infections, have been found to contribute to […]
September 5, 2018

UVA developing 'two – headed arrow' to kill ovarian cancer tumors

A University of Virginia School of Medicine researcher is developing a two-fisted, antibody-based approach to destroying deadly ovarian cancer – an approach he believes could also be modified to kill breast, prostate and other solid tumors. The dual-pronged approach that Jogender Tushir-Singh is developing aims to overcome obstacles that have undermined otherwise-promising […]
September 4, 2018

B Cells Among Factors Leading to Brain Lesions in Multiple Sclerosis

A team of researchers from UZH and USZ has shown that in multiple sclerosis, it is not only specific T cells that cause inflammation and lesions in the brain. B cells, a different type of immune cell, also play a role. These cells activate T cells in the blood. This […]
September 4, 2018

Exploring the matrix to uncover hidden drivers of ovarian cancer

To clump together and form living tissue, cells secrete molecules that create structure. But that structure isn’t always healthy, and understanding how it goes bad could reveal more about the way cancer develops. Those molecules, known as the extracellular matrix, do more than simply hold everything together. The extracellular matrix […]
September 4, 2018

Breeder meerkats age faster, but their subordinates still die younger

Despite rapidly ageing, dominant animals live longer because their underlings are driven out of the group – becoming easy targets for predators. The secret of a long meerkat life is to be “ruler of your community… cracking down on would-be rivals,” say scientists. In many cooperative species, the dominant breeders […]
September 4, 2018

Malaria vaccine work deploys parasite-fighting cells to liver

After an infected mosquito bite, malaria parasites travel from the bite site to the liver.  For that reason, the liver has become the target of numerous efforts to develop a potential vaccine. Currently there are no approved vaccines for people against any parasitic diseases, including malaria. Using a novel, liver-targeted […]
September 3, 2018

NEGTEC launches Crowdfunding Portal promoting Regenerative Medicine

Dream-Kicker.com to offer donation-based, cryptocurrency support for cutting-edge regenerative medicine and medical equipment. NEGTEC, originator of the Sakura Bloom (SKB) cryptocurrency project, has announced a new donation-based crowdfunding service and SKB-based web portal to promote the introduction of cutting-edge regenerative medicine and medical equipment to hospitals. The portal, Dream-Kicker.com, will […]
September 3, 2018

Dramatic development of immune system after birth

Examining how the neonatal immune system changes has been difficult since the analyses are made from samples taken from the umbilical cord directly after delivery. Researchers have now exploited a new technique of immune cell analysis to monitor how babies develop for the first few weeks of life outside the […]
September 3, 2018

Similar changes in the brains of patients with ADHD and emotional instability

Clinical attention has long been paid to the fact that individuals with ADHD also demonstrate emotional problems, such as chaotic emotional responses, anxiety and depression. Yet the relationship between ADHD and impaired emotional regulation has not been identified, even if theories have been proposed that both conditions are rooted in […]
September 3, 2018

Color-changing sensor detects signs of eye damage in tears

A new point-of-care rapid-sensing device can detect a key marker of eye injury in minutes – a time frame crucial to treating eye trauma. University of Illinois researchers developed a gel laden with gold nanoparticles that changes color when it reacts with a teardrop containing ascorbic acid, released from a […]
September 3, 2018

Treatment for severe heartburn prevents cancer

Pathological heartburn and acid reflux affects 10-20 per cent of the adult population. Long and severe reflux is the strongest risk factor for cancer of the oesophagus (type adenocarcinoma), an aggressive cancer that is difficult to treat. Reflux is usually treated with medicine to make the stomach contents less acidic, […]
September 3, 2018

Artificial Cells Are Tiny Bacteria Fighters

“Lego block” artificial cells that can kill bacteria have been created by researchers at the University of California, Davis Department of Biomedical Engineering. The work was reported in the journal ACS Applied Materials & Interfaces. “We engineered artificial cells from the bottom-up – like Lego blocks – to destroy bacteria,” said Assistant […]
September 3, 2018

The link between obesity, the brain, and genetics

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research. The study, led by researchers at the Montreal Neurological Institute and Hospital (The Neuro) and published in the Proceedings of […]
September 3, 2018

Researchers uncover hidden player in gut growth

A previously ignored part of the intestine has turned into the key to its most crucial moment in embryonic development: the rotation that winds the small and large intestine into its familiar twisted form. Where and how this rotation is triggered is the subject of new research from Natasza Kurpios’ […]
September 3, 2018

Scientists identify 35 genes associated with cannabis use

The study, conducted by a team of scientists, including Professor Marcus Munafo and Dr Jorien Treur from Bristol's School of Psychological Science, who are part of the International Cannabis Consortium, is the largest to date genetic study to look at the use of cannabis. Researchers used data from the UK Biobank, association results from 23andMe […]
August 31, 2018

Chronic Inflammation Can Trigger Cancers Via Newly Discovered Mechanism

It is well known that extended exposure to the sun’s UV rays can cause DNA mutations that lead to skin cancer. Now new research reveals that inflammation from chronic skin injury can trigger cancer-causing mutations as well by a totally distinct mechanism. The researchers – led by scientists at UC […]
August 31, 2018

Risk of Heart Attacks is Double for Daily E-Cigarette Users

Use of e-cigarettes every day can nearly double the odds of a heart attack, according to a new analysis of a survey of nearly 70,000 people, led by researchers at UC San Francisco. The research also found that dual use of e-cigarettes and conventional cigarettes – the most common use […]
August 31, 2018

Genetic tools uncover cause of childhood seizure disorder missed by other methods

Early childhood seizures result from a rare disease that begin in the first months of life. Researchers at University of Utah Health have developed high-tech tools to uncover the genetic cause of the most difficult to diagnose cases. The results are available online in the journal Nature Genomic Medicine. “These tools […]
August 30, 2018

New Therapy for Rare Lymphoma

A drug called mogamulizumab significantly improved progression-free survival for patients with cutaneous T-cell lymphoma, according to the results of a clinical trial published in The Lancet Oncology. The findings led to the FDA’s recent approval of the drug. “For patients affected by this debilitating disease, we can now offer a novel and effective treatment […]