General

The first complete human reference genome, which can serve as a template for sequencing DNA, corrects errors in the previous reference such as missing or misplaced genetic code. Alongside the newly updated human genome, which fills in long-standing gaps to fully spell out the more than 3 billion letters that […]

Partial reprogramming exposes senescent cells to the Yamanaka factors for long enough to reset their epigenetic patterns to those of a youthful cell, but not so long as to force a change of state into induced pluripotent stem cells. This is an active area of research, not yet an exact […]

The mixing of mitochondrial DNAs (mtDNAs) of two distinct origins can have damaging medium- and long-term effects, according to the results of a new study published in Circulatio. Research carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that mixing mitochondrial DNAs (mtDNAs) of different origins can […]