Study links caesareans and cardiovascular risk – Innovita Research

A new study has found that Australian children born via cesarean section (C-section) have a greater risk of cardiovascular disease and obesity, and it’s sparked a call to limit the increasingly popular practice.

Image credit: Piqsels, CC0 Public Domain

Dr Yaqoot Fatima from James Cook University’s Murtupuni Centre for Rural and Remote Health and Dr Tahmina Begum from the University of Queensland were part of a team that used data from the Longitudinal Study of Australian Children to analyse the health outcomes of children delivered by C-section.

“C-section births have risen worldwide disproportionately higher in developed countries. In Australia, the C-section birth rate has increased from 18.5 percent in 1990 to 36 per cent in 2019 and nearly half of Australian babies are projected to be caesarean born by 2045,” said Dr Begum.

She said the study found a relationship between C-section births and children's cardiovascular disease (CVD) risk factors.

“Four out of six individual CVD risk components and the composite index of the five CVD risk components showed a positive association with C-section birth. Our study also provided a direct relationship between C-section and increased overweight and obesity among children aged 10-12 years,” said Dr Fatima.

She said there was a biologically plausible reason for linking C-sections to CVD risk factors and obesity.

“There’s an altered microbial load from C-section birth as compared to vaginal birth. This altered microbial ecosystem hampers the ‘gut-brain axis’ and releases some pathogenic toxins that cause metabolic damage,” said Dr Begum.

She said it was also possible the fetal stress from physiological or pharmacological induction of labour during a C-section could also have an effect.

“In Australia in 2020, around 26 percent of deaths per year in the adult population were due to CVD. Globally, the chronic disease spectrum of CVDs costs trillions due to health service-related expenditures and loss of economic productivity,” said Dr Fatima.

She said the study provides important insights into health care policy and the strategic direction towards chronic disease risk reduction.

“Growing rates of C-sections conducted for non-clinical reasons is a major public health concern that calls for a reduction in the rate of unnecessary C-sections and their associated human and economic costs,” said Dr Begum.

Source: James Cook University