Robot – Page 119 – Innovita Research
May 20, 2021

New findings provide hope for treatment of multiple myeloma

Researchers at Karolinska Institutet have investigated the use of low dose venetoclax, an experimental drug, for the treatment of the heterogeneous cancer disease multiple myeloma in patients who had relapsed on standard therapies. The findings are published in the American Journal of Hematology and provide new hope for the treatment […]
May 20, 2021

Good results with online CBT for atopic eczema

The common skin disease atopic eczema (AE) impacts heavily on the life quality and general health of sufferers. Researchers at Karolinska Institutet have now evaluated its treatment with internet-delivered cognitive behavioural therapy (iCBT). The study suggests that patients feel better after iCBT compared with a control group who received only […]
May 20, 2021

New study shows flies mutant for schizophrenia-associated genes respond well to anti-psychotics

Scientists at Bristol have successfully treated flies displaying behavioural problems linked to newly discovered schizophrenia-associated genes in humans, using common antipsychotics. Schizophrenia is a severe long-term mental health condition that is historically poorly understood and treated. It is relatively common, affecting one to two per cent of the population, and […]
May 20, 2021

The microenvironment of breast cancer in three dimensions

Cancerous tumors thrive on blood, extending their roots deep into the fabric of the tissue around them. They alter the genetics of surrounding cells and evolve to avoid the protective attacks of immune cells. Now, Penn State researchers have developed a way to study the relationship between solid, difficult-to-treat tumors and the […]
May 20, 2021

A complex link between body mass index and Alzheimer’s

Though obesity in midlife is linked to an increased risk for Alzheimer’s disease, new research suggests that a high body mass index later in life doesn’t necessarily translate to greater chances of developing the brain disease. In the study, researchers compared data from two groups of people who had been […]
May 20, 2021

Dementia risk factors similar for men and women, but not high blood pressure

Differences in how blood pressure affects the risk of dementia in men and women may provide clues to help slow the rapid growth of the disease, according to new research published today. In a study of just over half a million people, George Institute researchers found that while the link between […]
May 19, 2021

The Great Good of Greater Healthy Longevity

It is a strange world that we live in, in which we have to argue – actually debate with people who earnestly hold the opposing view – that more of us living for longer, in better health than is the case today, is a good outcome. That it is worth […]
May 19, 2021

Spread of Breast Cancer Linked to Newly Discovered RNA Splicing Mechanism

What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to different organs. In comparison to what is already known about specific mutations that drive early-stage cancer growth […]
May 19, 2021

In a first, gut microbe genes linked to array of human diseases

We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome. In recent years, the mix of these resident bacteria, and the presence of specific bacterial species, has been linked to […]
May 19, 2021

Handheld laser devices could help evaluating liver for transplant

Organ transplant is saving millions of lives every year. However, many people continue waiting for the right donor. Some organs, sadly, get rejected as unsuitable for donation, but this decision is not easy to make. Now scientists from the University of Edinburgh, the Edinburgh Transplant Centre and the University of […]
May 19, 2021

The New Age to Get Your Colorectal Cancer Screening

An independent group of experts that advises the nation on preventive medical services has lowered the recommended age for adults to begin regular screenings for colorectal cancer from 50 to 45. The U.S. Preventive Services Task Force has given this recommendation for people without symptoms who are at average risk […]
May 19, 2021

Of Mice and Men: Mutation Linked to Autism Impairs Oxytocin-Mediated Social Behavior

A rare mutation in the Caps2 gene, which encodes a protein that regulates the release of brain chemicals called neurotransmitters, has also been linked with autism spectrum disorders. Now, researchers at the Tokyo University of Science report that Caps2 mutations in mice limit the release of oxytocin (a hormone that regulates social behavior), causing […]
May 18, 2021

Researchers Develop First-in-Class Inhibitors Against Key Leukemia Protein

The protein made by the ASH1L gene plays a key role in the development of acute leukemia, along with other diseases. The ASH1L protein, however, has been challenging to target therapeutically. Now a team of researchers led by Jolanta Grembecka, Ph.D., and Tomasz Cierpicki, Ph.D., from the University of Michigan has developed first-in-class small molecules […]
May 18, 2021

With a $4.3 million NASA grant, team aims disentangle the origins of protein translation

With support from a $4.3 million National Aeronautics and Space Administration (NASA) grant, the University of Minnesota will be the home of a new Interdisciplinary Consortium for Astrobiology Research (ICAR) program that explores the origins of life. Led by Burckhard Seelig, an associate professor in the College of Biological Sciences, the global […]
May 18, 2021

Reviewing Recent Work on the Mechanisms of Cellular Senescence

Impressive results have been produced in mice via clearance of senescent cells: rejuvenation, extension of life, and reversal of numerous different age-related conditions. This has provoked an increasing number of research groups to focus on the mechanisms of cellular senescence, in search of novel ways to identify and destroy these […]
May 18, 2021

Compound may prevent risk of form of arrhythmia from common medications

Dozens of commonly used drugs, including antibiotics, anti-nausea and anticancer medications, have a potential side effect of lengthening the electrical event that triggers contraction, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome. While safe in their current dosages, some of these drugs may have a more […]
May 18, 2021

Triple-negative breast cancer more deadly for African American women

Multiple studies have shown that African American women with breast cancer have lower survival rates than white women with the disease. But the association between race or ethnicity and treatment outcomes in triple-negative breast cancer — an aggressive type of tumor that does not respond to hormonal or other targeted […]
May 18, 2021

New Technology Makes Tumor Eliminate Itself

A new technology developed by UZH researchers enables the body to produce therapeutic agents on demand at the exact location where they are needed. The innovation could reduce the side effects of cancer therapy and may hold the solution to better delivery of Covid-related therapies directly to the lungs. Scientists […]
May 18, 2021

Tailored, earlier cardiac rehab program shows physical, emotional benefits for heart failure patients

An innovative cardiac rehabilitation intervention started earlier and more custom-tailored to the individual improved physical function, frailty, quality-of-life, and depression in hospitalized heart failure patients, compared to traditional rehabilitation programs. Supported by the National Institute on Aging (NIA), part of the National Institutes of Health, these new study results were published […]
May 18, 2021

Researchers Discover First Immune Stimulating Long Noncoding RNA Involved in Body's Response to Cancer

A long noncoding RNA whose function was previously unknown turns out to play an important role in promoting the body’s immune response against cancer and holds promise for enhancing the efficacy of anti-cancer immunotherapy. That’s according to new findings reported in Nature Cell Biology by researchers at the University of Michigan Rogel Cancer Center. […]
May 18, 2021

New study on vitamin B₃ as a possible treatment for glaucoma

Glaucoma involves a high risk of losing sight. Researchers at Karolinska Institutet and St. Erik Eye Hospital, among others, have now studied the effects of nicotinamide, the amide of vitamin B₃, on animal and cell models for glaucoma. The study, published in Redox Biology, maybe a future neuroprotective therapy in […]
May 18, 2021

Study finds evidence of persistent Lyme infection in brain despite aggressive antibiotic therapy

Tulane University researchers found the bacterium that causes Lyme disease in the brain tissue of a woman who had long suffered neurocognitive impairment after her diagnosis and treatment for the tick-borne disease. The presence of the corkscrew-shaped Borrelia burgdorferi spirochetes in the former Lyme disease patient’s brain and spinal cord were evidence […]
May 18, 2021

Shortcut for dendritic cells

During an inflammatory response, things need to happen quickly: ETH Zurich researchers have recently discovered that certain immune cells that function as security guards can use a shortcut to get from the tissue to lymph nodes. In its response to pathogens and vaccines, our immune system relies on dendritic cells. […]
May 17, 2021

The Freshwater Fish Species of Bigmouth Buffalo Exhibits Negligible Senescence

The individual members of a very small number of species are functionally immortal. These are all lower animals that exhibit a profound capacity for regeneration and lack sophisticated nervous systems, such as hydra or jellyfish. A hydra is essentially a hunger-motivated bundle of stem cells, at least from the perspective […]
May 17, 2021

Bio-inspired scaffolds help promote muscle growth

Rice University bioengineers are fabricating and testing tunable electrospun scaffolds completely derived from decellularized skeletal muscle to promote the regeneration of injured skeletal muscle. Their paper in Science Advances shows how natural extracellular matrix can be made to mimic native skeletal muscle and direct the alignment, growth and differentiation of myotubes, one of the building […]
May 17, 2021

Novel Gene Identified as Genetic Cause of Portal Hypertension

The liver serves many critical functions within the human body, including the production of critical proteins, and the removal of waste and toxins. But when damage occurs to the largest organ in the body, many people do not experience symptoms until serious damage has occurred. When the liver becomes scarred, […]
May 17, 2021

New research optimizes body’s own immune system to fight cancer

A groundbreaking study led by engineering and medical researchers at the University of Minnesota Twin Cities shows how engineered immune cells used in new cancer therapies can overcome physical barriers to allow a patient’s own immune system to fight tumors. The research could improve cancer therapies in the future for […]