June 15, 2021

Osteoporosis: New Approach to Understanding Bone Strength Pays Dividends

Researchers at the University of Virginia School of Medicine have taken a new approach to understanding how our genes determine the strength of our bones, allowing them to identify several genes not previously known to influence bone density and, ultimately, our risk of fracture. The work offers important insights into […]
June 15, 2021

ALS: decoding its molecular mechanisms to improve treatment

Nearly 3,000 Canadians are living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot's disease. Each year, close to 1,000 people are diagnosed with ALS and as many will die from it. ALS is an incurable neurodegenerative disorder characterized by the selective loss of motor neurons. […]
June 15, 2021

A Frozen Leap Forward

Scientists at UC Santa Barbara, University of Southern California (USC), and the biotechnology company Regenerative Patch Technologies LLC (RPT) have reported new methodology for the preservation of RPT’s stem cell-based therapy for age-related macular degeneration (AMD). The new research, recently published in Scientific Reports(link is external), optimizes the conditions to cryopreserve, […]
June 15, 2021

Toward the first drug to treat a rare, lethal liver cancer

Treatment options for a deadly liver cancer, fibrolamellar carcinoma, are severely lacking. Drugs that work on other liver cancers are not effective, and although progress has been made in identifying the specific genes involved in driving the growth of fibrolamellar tumors, these findings have yet to translate into any treatment. […]
June 15, 2021

Study finds brain areas involved in seeking information about bad possibilities

The term “doomscrolling” describes the act of endlessly scrolling through bad news on social media and reading every worrisome tidbit that pops up, a habit that unfortunately seems to have become common during the COVID-19 pandemic. The biology of our brains may play a role in that. Researchers at Washington […]
June 15, 2021

Mathematics to improve macular degeneration treatment

Age-related macular degeneration (AMD) is a degenerative disease of the macula, the central area of the retina. There is currently no cure for the disease and it is characterised by a gradual loss of central vision and is the leading cause of blindness in developed countries in people over the […]
June 15, 2021

Teams Engineer Complex Human Tissues, Win Top Prizes in NASA Challenge

Two teams of scientists from the Wake Forest Institute for Regenerative Medicine (WFIRM) in Winston-Salem, North Carolina, have won first and second place in NASA's Vascular Tissue Challenge. The prize competition aims to accelerate tissue engineering innovations to benefit people on Earth today and space explorers in the future. Competing as teams […]
June 15, 2021

Scientists deploy creativity, speed to disrupt COVID-19

In early 2020, when the novel coronavirus was gaining momentum but had not yet been named a pandemic, computational chemist Marti Head of Oak Ridge National Laboratory – along with scientists and researchers around the globe – abruptly switched her focus to the fight against COVID-19. The world was struggling to understand this new […]
June 14, 2021

They build proteins that are not known to nature

Using chemical synthesis, Bright Peak Therapeutics can produce proteins that have never before existed. This holds great potential for cancer immunotherapy. The Basel-​based spin-off has its beginnings at ETH Zurich. Jeffrey Bode’s long, bold journey began over an after-work beer in Tokyo. A biologist friend said to the then postdoc, […]
June 14, 2021

Single Injection, Broad Protection

Vaccine generates robust immune responses against SARS-CoV-2 variants. In the three months since Johnson & Johnson’s COVID-19 vaccine was granted an emergency use authorization from the U.S. Food and Drug Administration, more than 10 million Americans have received the vaccine, according to the U.S. Centers for Disease Control and Prevention. […]
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