Robot – Innovita Research
February 25, 2021

Basic cell health systems wear down in Huntington’s disease, analysis shows

A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis. Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington’s disease may progress to advanced […]
February 25, 2021

Critical step forward for radiotherapy with a new method to treat cancer

A new research development from The University of Manchester and The Christie NHS Foundation Trust has shown progress for developing a potential new cancer treatment using high energy electron beams. The collaborative research team have published their findings in Nature’s journal, Scientific Reports, and demonstrated that Very High Energy Electron (VHEE) beams can have […]
February 25, 2021

Using predictive biomarkers could improve success rate of new cancer drugs

In recent decades, researchers have made big advances in developing new cancer medicines such as Herceptin, the targeted drug to treat women diagnosed with HER2-positive breast cancer. Yet, despite these successes, cancer remains the second leading cause of death after heart disease and nearly 90 per cent of all cancer drugs entering […]
February 25, 2021

"Good bacteria" in breast milk changes over time

The cocktail of beneficial bacteria passed from mother to infant through breast milk changes significantly over time and could act like a daily booster shot for infant immunity and metabolism. The research, conducted by scientists from Montreal and Guatemala and published in Frontiers in Microbiology, has important implications for infant development […]
February 25, 2021

From out of the blue comes a better bladder-cancer detector

Decades ago, blue lights helped shoppers scope out sales. Today they’re helping urologists scope out cells, specifically those of non-muscle-invasive bladder cancer. UW Medicine urologists with the Seattle Cancer Care Alliance possess a mechanism that makes the tumors glow bright pink. All the better to see them. “Seventy percent of bladder […]
February 25, 2021

Penn Scientists Discover Microbial Transplants Require Key T Cells for Success

Scientists have known for more than a decade that “good bacteria” from healthy intestines can treat and ward off potentially deadly intestinal infections by Clostridium difficile bacteria. Now researchers at the Perelman School of Medicine at the University of Pennsylvania have discovered that immune cells called Treg cells are crucial for the success […]
February 25, 2021

Fat cells may influence how the body reacts to heart failure, study shows

University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients. In a recent study published in the American Journal of Physiology, Jason Dyck, professor of paediatrics in the Faculty of Medicine & Dentistry and director […]
February 25, 2021

Seeing schizophrenia: X-rays shed light on neural differences, point toward treatment

An international research team used the ultrabright X-rays of the Advanced Photon Source to examine neurons in the brains of schizophrenia patients. What they learned may help neurologists treat this harmful brain disorder. Schizophrenia, a chronic, neurological brain disorder, affects millions of people around the world. It causes a fracture […]
February 25, 2021

Reactivating Aging Stem Cells in the Brain

As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function. Researchers at the University of Zurich have now discovered a mechanism linked to stem cell aging – and how the production of neurons can be reactivated. […]
February 24, 2021

Challenge: Device to Address Calcified Coronary Arteries

NineSigma, representing a global 500 medical device company, invites proposals for technologies that can alleviate the deleterious effects of calcified coronary arteries in a manner that is both easier and safer than traditional angioplasty or atherectomy procedures. The goal of this RFP is to identify technologies, beyond those that are traditionally […]
February 24, 2021

Effective treatment for insomnia delivered in a few short phone calls

Insomnia — trouble falling asleep, staying asleep or waking up too early — is a common condition in older adults. Sleeplessness can be exacerbated by osteoarthritis, the most common form of arthritis causing joint pain. While there are effective therapies for treating insomnia in older adults, many people cannot get […]
February 24, 2021

Stroke of Luck: Scientists Discover Target for Stroke Therapy in Blood-Brain Barrier

The blood-brain barrier prevents immune cells from circulating freely in the brain, and the breakdown of its function is a major cause of post-stroke inflammation. Now, for the first time, researchers have identified how a toxic stroke byproduct, acrolein, could activate the barrier-degrading enzyme proheparanase (proHPSE). The research group has […]
February 24, 2021

High fructose diets could cause immune system damage

New research led by Swansea University in collaboration with researchers at the University of Bristol and the Francis Crick Institute in London has indicated that consuming a diet high in sugar fructose might prevent the proper functioning of peoples' immune systems in ways that have, until now, largely been unknown. […]
February 23, 2021

Sleep is vital to associating emotion with memory, according to U-M study

When you slip into sleep, it’s easy to imagine that your brain shuts down, but University of Michigan research suggests that groups of neurons activated during prior learning keep humming, tattooing memories into your brain. U-M researchers have been studying how memories associated with a specific sensory event are formed […]
February 23, 2021

An experimental neurofeedback imaging treatment has emerged for psychiatric patients. Does it work?

In recent years, researchers have begun using functional magnetic resonance imaging (fMRI) not just for better understanding the neural bases of psychiatric illness, but also for experimental treatment of depression, ADHD, anxiety, PTSD, substance use disorder, and schizophrenia with a technique called real-time fMRI neurofeedback. While rtfMRI-NF has emerged in recent […]
February 23, 2021

Yale scientists repair injured spinal cord using patients’ own stem cells

Intravenous injection of bone marrow-derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report in the Journal of Clinical Neurology and Neurosurgery. For more than half of the patients, substantial improvements in key functions — such […]
February 23, 2021

Toward a disease-sniffing device that rivals a dog’s nose

Numerous studies have shown that trained dogs can detect many kinds of disease —  including lung, breast, ovarian, bladder, and prostate cancers, and possibly Covid-19 — simply through smell. In some cases, involving prostate cancer, for example, the dogs had a 99 per cent success rate in detecting the disease […]
February 22, 2021

AI can predict f­fic­acy of breast cancer treat­ment from morphology of the tumour

Artificial Intelligence has a huge potential in diagnostic medicine. It can run through vast amounts of data very quickly, noticing details that escape the human eye. Now scientists from the University of Helsinki have demonstrated the possibilities to use AI to predict the efficacy of a targeted breast cancer therapy. […]
February 22, 2021

How do people without the sense of touch feel their body position?

One of the huge problems in developing self-propelled robots is awareness of the body positioning. We as humans and animals have that solved very well – we sense when we touch something and are very aware of the boundaries of our physical selves. But how – is sense of touch […]
February 22, 2021

New research on mitochondrial function can play significant part in serious disease

Disorders of the cells’ energy supply can cause a number of serious diseases, but also seem to be connected to ageing. More research is needed on a mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects […]
February 22, 2021

How a gene called HAND2 may impact the timing of labor

A new study illuminates how a gene called HAND2 may have a hand in the timing of human labour. “We don’t know why humans go into labour. It’s a basic aspect of human biology that we just don’t know the answer to, and it’s kind of embarrassing that we don’t,” […]
February 22, 2021

Five Years Later: Penn-developed CAR T Therapy Shows Long-lasting Remissions in Non-Hodgkin Lymphomas

Findings represent the longest follow-up data to date for a personalized cellular therapy approved by the FDA for the treatment of aggressive lymphomas. A significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical trial continue to be in remission five years after receiving the chimeric antigen receptor […]
February 22, 2021

Key Decision Point for Brain Development Identified

The brain — the central processor of all our thoughts, emotions, motivations and drives — is certainly our most elaborate organ, and is sometimes considered to be one of the most complicated objects in the universe. So it is one of the wonders of nature that this organ of ultimate […]
February 22, 2021

Study finds analyzing DNA in urine could help detect cancer

Currently, cancers are detected and diagnosed using more invasive methods such as surgical biopsies of suspected tumours and blood draws. Urinalysis has long been used to detect and manage many diseases and disorders, but not cancer. Researchers investigated whether fragments of cell-free DNA in urine could be analyzed to detect […]
February 22, 2021

Store Fat or Burn It? Targeting a Single Protein Flips the Switch

As obesity becomes a growing issue worldwide – nearly tripling over the last-half century – scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in […]
February 22, 2021

Developing a targeted delivery system to treat cancer

In the ongoing battle to find ways to treat cancer, a team at the University of Missouri is addressing the problem from multiple angles, but with a precision approach. Cancer patients are often given chemotherapy, cancer-fighting drugs that kill cancerous cells and can also have harsh effects on healthy cells. […]
February 20, 2021

Mediterranean-style diet can help you maintain the sharpness of your mind

Sharpness of your mind is definitely very important to you. And we all would like to stay sharp for as long as possible, although age-related dementia is in the cards for many. How can we avoid that? Scientists from the University of Edinburgh have found a way to maintain the […]
February 20, 2021

An mRNA vaccine for cancer immunotherapy

Messenger RNA (mRNA) vaccines to prevent COVID-19 have made headlines around the world recently, but scientists have also been working on mRNA vaccines to treat or prevent other diseases, including some forms of cancer. Now, researchers reporting in ACS’ Nano Letters have developed a hydrogel that, when injected into mice with […]
February 19, 2021

University of Alberta researchers launch program to diagnose genetic diseases in children

A new University of Alberta pilot program aims to find answers and better treatments for children living with rare genetic conditions. The Undiagnosed Disease Program, launched in January, is a collaboration between the Women and Children’s Health Research Institute (WCHRI) and U of A researchers from medical genetics and pediatric neurology to […]
February 19, 2021

Half of COVID-19 patients with raised levels of one protein experience heart damage

COVID-19 is a dangerous respiratory infection, which can lead to severe complications. One of such complications is heart damage. Scientists at UCL found that more than 50% of patients hospitalised with COVID-19, who had raised levels of a protein called troponin, have some heart damage. Having in mind that troponin […]