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A large, multi-institution study led by a Brown University physician-scientist could have important implications for the development of new classes of cancer therapeutics. Interrupting one function of a protein that plays a key role in cell signaling could enable the development of new cancer treatments, according to a study led […]

Patients who discontinue weight-loss medications see their progress vanish quickly, with comprehensive research revealing a concerning pattern of rapid reversal in both weight reduction and health improvements. Key Takeaways: Analysis of 9,341 patients across 37 studies examined outcomes from 18 different weight-loss medications. The data paints a clear picture: stopping […]

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University. The results may also explain why combining certain cancer drugs can produce the opposite of the intended effect. The […]

A blood pressure as low as 120/80 mm Hg in adolescence can be linked to a higher risk of atherosclerosis in middle age, according to a study led from Linköping University. The findings indicate that high blood pressure early in life plays an important role in the development of coronary […]

For years, scientists studying Parkinson’s and Alzheimer’s have been stuck with the same frustrating problem: the diseases happen deep inside the human brain, long before symptoms show up, and there has never been a reliable way to watch those earliest changes unfold. Animal models help, but they rarely behave exactly […]

Over the recent years Erastin has become an interesting small molecule in biomedical studies. Erastin is a chemical known mostly due to its capacity to cause a distinct type of cell death referred to as ferroptosis, which has captured interested among chemists, biologists, and medical researchers alike. Contrary to apoptosis […]

A previously unknown type of mitochondrial DNA damage could shed light on how our bodies sense and respond to stress. The findings of the UC Riverside-led study are published today in the Proceedings of the National Academy of Sciences and have potential implications for a range of mitochondrial dysfunction-associated diseases, including cancer […]

A consortium led by the University of Southampton has received funding to develop next-generation treatments for cancer and chronic inflammation. The consortium, made up of 10 academic research groups, four companies, a hospital and a non-profit organisation, has received £3.8 million from the Horizon Europe Marie Skłodowska-Curie Actions (MSCA) programme. […]

UCLA researchers have created the first single-cell map of how DNA is regulated and organized inside different cell types of human fat tissue. The study, published in Nature Genetics, shows that many genetic risk factors for abdominal obesity reside in epigenomic regions of fat cells, offering clues about how body […]

University of Warwick research demonstrates how to engineer ‘cell factories’ that last longer and produce more chemicals, without needing antibiotics or complex engineering methods, paving the way for sustainable biotech that lasts. Synthetic biology aims to engineer living cells, often bacteria, to become chemical factories, pumping out chemicals important to […]

For families of children with severe epilepsy, controlling seizures is often just the beginning of their challenges. Even in cases where powerful medications can reduce seizures, many children continue to face difficulties with learning, behavior and sleep that can be just as disruptive to daily life. New stem cell-based research […]