General

Researchers at Vanderbilt University Medical Center have discovered a new genetic disease that causes a severe form of neurogenic orthostatic hypotension, a rapid drop in blood pressure upon standing that can cause fainting. The rare condition, which they named familial autonomic ganglionopathy, is caused by variations in the CHRNA3 gene, […]

By studying guppies, scientists at the University of Toronto and Florida State University found that behaviours affected by methylphenidate hydrochloride (MPH) – the active ingredient in stimulants such as Ritalin and Concerta used to treat ADHD – can be passed along to several generations of descendants. “We exposed male and female Trinidadian […]

A new model by University of Manchester researchers has proposed a way to prevent hearing loss in older people by addressing socioeconomic inequalities encountered while young. Published in Trends in Hearing the team hope the model could impact the estimated 466 million people worldwide who have disabling hearing loss, mostly affecting […]

Women may have a stronger immune response to a common form of skin cancer than men, according to early research on mice and human cells. Led by University of Manchester scientists at the Cancer Research UK Manchester Institute, the team publish their findings in Clinical Cancer Research. The study is funded by The Wellcome […]

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), which then divide into precursor cells that eventually become neurons. A team from the University of Michigan, spearheaded by graduate […]

The University of Michigan is one of eight sites around the country that will enroll patients in a clinical trial to evaluate the safety and efficacy of a technology that uses ultrasound to treat liver tumors. The #HOPE4LIVER trial will employ the noninvasive technique to mechanically destroy primary and metastatic liver tumors. […]

It’s long been known that people living with HIV experience a loss of white matter in their brains. As opposed to grey matter, which is composed of the cell bodies of neurons, white matter is made up of a fatty substance called myelin that coats neurons, offering protection and helping […]

A lot of people are trying to lose some weight. Some just want to look better for the summer, others are fighting for better health and well-being. Losing weight is not easy and many people find themselves gaining weight soon after losing it. What makes it difficult to maintain a […]

Meningiomas are the most common type of primary brain tumor. Found in the meninges– or the tissue that surrounds the brain and spinal cord, meningiomas are often benign. However, some can behave more aggressively and recur. These tumors can affect critical neurovascular structures, such as arteries and cranial nerves, impacting […]

While some people find it unsightly, scarring is actually quite an interesting thing. Scar tissue is harder and more resilient and its formation is one of the body’s natural functions. However, scars can also be quite uncomfortable or even painful. Now scientists at the University of Queensland have found a […]

Researchers have developed antibodies that can bind to phosphohistidine, an unstable molecule that’s linked to cancer. To learn how the two bind together, the team turned to the powerful X-rays at Argonne’s Advanced Photon Source. Scientists are harnessing hard X-rays in the fight against cancer. A team of researchers, in […]

The goal of modern cancer treatments is to kill off cancer cells while causing the least amount of damage to the surrounding tissue. This is not easy to do with current therapies, which often cause significant side effects. Now researchers at the University of Edinburgh have tested new light-activated drugs […]

We are trying to see the end of the COVID-19 pandemic. It feels like it’s been so long since we could gather and partake in our usual social activities without the fear of spreading this dangerous disease. Maybe summer will help lift some of the burden of COVID-19 spread? Scientists […]

To analyze the genome or the genetic characteristics of a living organism, scientists typically rely on samples of millions of cells. The problem is that the DNA in each of our cells is not identical. Until recently, the amount of DNA that could be extracted from a single cell couldn’t […]

Human cell has 46 chromosomes. From your school biology class you know that they contain instructions for life – your DNA is in them. And while we know about chromosomes for 130 years there are still many details that have escaped scientists’ eyes for decades. For example, scientists at UCL […]

A research team led by scientists at Université de Montréal has developed a unique observational tool for assessing children up to 5 years of age who have had a concussion. The work is explained in a study published in the Journal of Head Trauma Rehabilitation. Pediatric traumatic brain injury (TBI) is particularly […]

Antibodies aren’t the only immune cells needed to fight off COVID-19 — T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine. The researchers found that blood cancer patients with COVID-19 […]

A protein involved in cholesterol metabolism plays a previously unknown role in suppressing the body’s natural immune defenders in and around pancreatic tumours, research led by the University of Michigan Rogel Cancer Center finds. ApoE, an apolipoprotein known to play roles in cardiovascular disease and Alzheimer’s, is elevated in the blood of people […]

A clinical trial examining the efficacy of two devices to monitor and detect atrial fibrillation (AF), or an irregular heartbeat, in ischemic stroke patients—one an implantable device that monitors over 12 months, the other an external device that monitors over a 30-day period—found the implantable device is more than three […]

Getting enough sleep can be a real challenge for shift workers affecting their overall health. But what role does being an early bird or night owl play in getting good rest? Researchers from McGill University find a link between chronotype and the amount of sleep shift workers can get with […]

Infant malnutrition damages the composition of intestinal bacteria, the microbiome. It has life-long consequences on the physical and intellectual development of affected children. Using pigs and mice models, Professor Bernard Henrissat from DTU Bioengineering in collaboration with the Washington University School of Medicine (USA), shows that damage to the microbiome […]

As anyone who has ever procrastinated knows, remembering that you need to do something and acting on that knowledge are two different things. To understand how learning changes nerve cells and leads to different behaviors, researchers studied the much simpler nervous system of worms. “In this study, we can now […]

The human papillomavirus (HPV) can cause cancer and many countries run national vaccination programmes to minimise the risk. Studies involving researchers at German Cancer Research Center, Karolinska Institutet and Tampere University now report on the longitudinal effect of common HPV vaccines. The results, which are published in The Journal of […]

We all need sleep to properly function and live. Not getting enough sleep harms our well-being, health, and immunity. Even one sleepless night can affect our bodies. Today's times do not have a positive effect on proper sleep and its sufficient amount. Work-related stress, irregular lifestyle, overwhelming responsibilities, or mental […]

A massive genome-wide association study (GWAS) of genetic and health records of 1.2 million people from four separate data banks has identified 178 gene variants linked to major depression, a disorder that will affect one of every five people during their lifetimes. The results of the study, led by the U.S. Department […]

A University of Alberta spinoff company has received FDA approval for an artificial intelligence tool that could revolutionize thyroid ultrasounds, making the procedure faster and easier for thousands of Canadians who undergo it each year. MEDO.ai, with offices in Edmonton and Singapore, received approval last month from the U.S. Food […]

Swiftness is essential when treating lung cancer, the second most common type of cancer in the U.S. and the country’s leading cause of cancer deaths. For patients with early-stage non-small cell lung cancer, surgical removal of a tumour-infested lung or of a smaller lung section may be the only treatment […]

Miniaturized chips containing live, human kidney cells will be on board the scheduled June 3 Space X cargo supply Mission 22 to the International Space Station.  Inside the 3D chips, the cells are kept alive in a tiny system that delivers fluids dynamically.  These tissue chips model responses that take […]

Project to classify nuclei across the tree of life discovers how to transmute them from one type into another. One hundred fifty years ago, Dmitri Mendeleev created the periodic table, a system for classifying atoms based on the properties of their nuclei. This week, a team of biologists studying the tree of life […]

Researchers from ETH Zurich and University of Zurich have developed a new microscopy technique that lights up the brain with high resolution imagery. This allows neuroscientists to study brain functions and ailments more closely and non-​invasively. The way the human brain works remains, to a great extent, a topic of […]