May 20, 2021

Dementia risk factors similar for men and women, but not high blood pressure

Differences in how blood pressure affects the risk of dementia in men and women may provide clues to help slow the rapid growth of the disease, according to new research published today. In a study of just over half a million people, George Institute researchers found that while the link between […]
May 19, 2021

The Great Good of Greater Healthy Longevity

It is a strange world that we live in, in which we have to argue – actually debate with people who earnestly hold the opposing view – that more of us living for longer, in better health than is the case today, is a good outcome. That it is worth […]
May 19, 2021

Spread of Breast Cancer Linked to Newly Discovered RNA Splicing Mechanism

What kills most people who die from cancer is not the initial tumor. It’s the intolerable disease burden on the body that arises when tumor cells continually expand their numbers after spreading to different organs. In comparison to what is already known about specific mutations that drive early-stage cancer growth […]
May 19, 2021

In a first, gut microbe genes linked to array of human diseases

We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome. In recent years, the mix of these resident bacteria, and the presence of specific bacterial species, has been linked to […]
May 19, 2021

Handheld laser devices could help evaluating liver for transplant

Organ transplant is saving millions of lives every year. However, many people continue waiting for the right donor. Some organs, sadly, get rejected as unsuitable for donation, but this decision is not easy to make. Now scientists from the University of Edinburgh, the Edinburgh Transplant Centre and the University of […]
May 19, 2021

The New Age to Get Your Colorectal Cancer Screening

An independent group of experts that advises the nation on preventive medical services has lowered the recommended age for adults to begin regular screenings for colorectal cancer from 50 to 45. The U.S. Preventive Services Task Force has given this recommendation for people without symptoms who are at average risk […]
May 19, 2021

Of Mice and Men: Mutation Linked to Autism Impairs Oxytocin-Mediated Social Behavior

A rare mutation in the Caps2 gene, which encodes a protein that regulates the release of brain chemicals called neurotransmitters, has also been linked with autism spectrum disorders. Now, researchers at the Tokyo University of Science report that Caps2 mutations in mice limit the release of oxytocin (a hormone that regulates social behavior), causing […]
May 18, 2021

Researchers Develop First-in-Class Inhibitors Against Key Leukemia Protein

The protein made by the ASH1L gene plays a key role in the development of acute leukemia, along with other diseases. The ASH1L protein, however, has been challenging to target therapeutically. Now a team of researchers led by Jolanta Grembecka, Ph.D., and Tomasz Cierpicki, Ph.D., from the University of Michigan has developed first-in-class small molecules […]
May 18, 2021

With a $4.3 million NASA grant, team aims disentangle the origins of protein translation

With support from a $4.3 million National Aeronautics and Space Administration (NASA) grant, the University of Minnesota will be the home of a new Interdisciplinary Consortium for Astrobiology Research (ICAR) program that explores the origins of life. Led by Burckhard Seelig, an associate professor in the College of Biological Sciences, the global […]
May 18, 2021

Reviewing Recent Work on the Mechanisms of Cellular Senescence

Impressive results have been produced in mice via clearance of senescent cells: rejuvenation, extension of life, and reversal of numerous different age-related conditions. This has provoked an increasing number of research groups to focus on the mechanisms of cellular senescence, in search of novel ways to identify and destroy these […]