February 28, 2021

Healing with hydrogels

Inspired by personal tragedy, graduate student Hyunwoo Yuk used his background in soft materials to develop a bioadhesive tape for repairing damaged tissue. In November, mechanical engineering PhD candidate Hyunwoo Yuk earned the top prize at the Collegiate Inventors Competition hosted by the National Inventor’s Hall of Fame. Yuk was […]
February 28, 2021

New type of bone cell could reveal targets for osteoporosis treatment

Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may reveal new therapeutic approaches for osteoporosis and other skeletal diseases. The new cells, which the researchers term ‘osteomorphs’, are found in the blood and bone marrow, and fuse together to form osteoclasts, […]
February 28, 2021

Study: fading memories make childhood trauma research a challenge in adults

A new study from the University of Iowa finds that the limitations of human memory make it difficult for researchers to link adverse childhood experiences to physical health issues later in life. The researchers found that so many people either forget what happened to them in childhood or don’t remember it […]
February 28, 2021

Vanderbilt-developed obesity treatments will be advanced through collaboration with Soleno Therapeutics

A new partnership between Vanderbilt University’s Warren Center for Neuroscience Drug Discovery and clinical-stage biopharmaceutical company Soleno Therapeutics will further research into new clinical treatments for multiple obesity syndromes. Leading the collaboration are WCNDD director Craig Lindsley, who holds the William K. Warren, Jr. Chair in Medicine, and Jerod Denton, professor of anesthesiology and pharmacology […]
February 28, 2021

New Model Predicts Cancer Drug Efficacy Across and Within Cancer Types

The goal of “precision oncology” is to be able to tailor treatments to each individual patient based on their cancer’s unique molecular fingerprints. New technologies and large, “-omics” datasets are now allowing researchers to examine shared features not just within a single type of cancer — such as breast cancer […]
February 27, 2021

Identification of ‘violent’ processes that cause wheezing could lead to better diagnosis and treatment for lung disease

A team of engineers has identified the ‘violent’ physical processes at work inside the lungs which cause wheezing, a condition that affects up to a quarter of the world’s population. The researchers, from the University of Cambridge, used modelling and high-speed video techniques to show what causes wheezing and how […]
February 27, 2021

Researchers detect key flaw in brain modeling

A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center. The cell, known as an induced […]
February 27, 2021

Fungi in the gut prime immunity against infection

Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections. The study, published in Cell, reveals a new twist […]
February 27, 2021

Tumor microenvironment helps aggressive lymphomas

The environment surrounding the cancerous cells of a lymphoma tumor has a strong influence on the progression of these blood-cell cancers and their responses to therapies, according to a new study by Weill Cornell Medicine investigators. Measuring this molecular and cellular environment, or “microenvironment,” appears to represent a new type […]
February 27, 2021

Study finds ‘Achilles’ heel’ of Crohn’s-linked bacteria

The discovery of an “Achilles’ heel” in a type of gut bacteria that causes intestinal inflammation in patients with Crohn’s disease may lead to more targeted therapies for the difficult-to-treat disease, according to researchers at Weill Cornell Medicine and NewYork-Presbyterian. In a study published in Cell Host and Microbe, the investigators showed […]
February 27, 2021

Gene critical to immune cell development identified

Much of the three-dimensional architecture of the genome in antibody-producing immune cells is dependent on a gene called SMC3. When this gene is not working properly it can lead to improper immune cell development and to cancer, by disrupting how DNA is structured inside the cell nucleus, according to a […]