July 27, 2021

'Zombie cells' hold clues to spinal cord injury repair

Mammals have a poor ability to recover after a spinal cord injury which can result in paralysis. A main reason for this is the formation of a complex scar associated with chronic inflammation that produces a cellular microenvironment that blocks tissue repair. Now, a research team led by Leonor Saude, […]
July 26, 2021

Castration Delays Epigenetic Aging in Male Sheep

Castration is known to extend life in male sheep. Researchers here show that epigenetic clocks constructed for this species show the expected slowing of epigenetic aging following castration. This is a way to dig deeper into the question of how it is that females live longer than males in mammalian […]
July 26, 2021

Largest-Ever Type 1 Diabetes Genetic Study Identifies Potential Treatment Targets

Scientists have completed the largest and most diverse genetic study of Type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults. Several potential drugs are already in the pipeline. Drugs targeting 12 genes identified in the diabetes study have been tested […]
July 26, 2021

Discovery of Unknown Brain-Repair Process Could Lead to New Epilepsy Treatments

University of Virginia School of Medicine researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries. Common seizure-preventing drugs do not work for approximately a third of epilepsy patients, so new and better treatments for such […]