February 27, 2021

Genetics May Play Role in Determining Immunity to COVID-19

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines. In a PLOS ONE paper researchers at University of California San Diego School of Medicine report that individual immune […]
February 27, 2021

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

UC San Diego researchers will inject harmless virus carrying a restorative gene into participants’ brains, where earlier animal studies suggest it may slow, prevent or reverse progression of the neurological disorder. Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to […]
February 27, 2021

Last-Itch Effort: Fighting the Bacteria That Exacerbate Eczema with Bacteria

In a new study out of University of California San Diego School of Medicine, researchers have identified a universal strain of bacteria derived from healthy human skin that can treat the most common type of eczema, also known as atopic dermatitis. In the paper published in Nature Medicine, the research […]
February 27, 2021

A new way beckons to treat severe obesity

New research by a prestigious Université de Montréal researcher could pave the way for the treatment of early morbid familial obesity, a disease that affects four to six per cent of people suffering from early severe obesity. Co-authored by Michel Bouvier and Patricia René of UdeM’s Institute for Research in […]
February 27, 2021

Bioinformatics tool accurately tracks synthetic DNA

Tracking the origin of synthetic genetic code has never been simple, but it can be done through bioinformatic or, increasingly, deep learning computational approaches. Though the latter gets the lion’s share of attention, new research by computer scientist Todd Treangen of Rice University’s Brown School of Engineering is focused on whether sequence alignment and pan-genome-based methods can outperform recent […]
February 27, 2021

Weill Neurohub joins with Genentech, Roche to advance neuroscience research

The University of California, San Francisco (UCSF) and UC Berkeley announced a long-term research partnership with Genentech, a member of the Roche Group, and its parent company, Roche Holding AG, to speed the development of new therapeutics for debilitating brain diseases and disorders of the central nervous system (CNS), such […]
February 26, 2021

Researchers take an early step toward leukemia drug therapy

A McMaster stem cell research team has made an important early step in developing a new class of therapeutics for patients with a deadly blood cancer. The team has discovered that for acute myeloid leukemia (AML) patients, there is a dopamine receptor pathway that becomes abnormally activated in the cancer […]
February 26, 2021

Scientists capture the choreography of a developing brain

The formation of a brain is one of nature’s most staggeringly complex accomplishments. The intricate intermingling of neurons and the labyrinth of connections also make it a particularly difficult feat for scientists to study. Now, Yale researchers and collaborators have devised a strategy that allows them to see this previously […]
February 26, 2021

New strategy blocks chronic lung disease in mice

Inflammatory lung diseases such as asthma, COPD and, most recently, COVID-19, have proven difficult to treat. Current therapies reduce symptoms and do little to stop such diseases from continuing to damage the lungs. Much research into treating chronic inflammatory diseases has focused on blocking chemicals called cytokines, which trigger cascades […]
February 26, 2021

New experiences enhance learning by resetting key brain circuit

A study of spatial learning in mice shows that exposure to new experiences dampens established representations in the brain’s hippocampus and prefrontal cortex, allowing the mice to learn new navigation strategies. The study, published in Nature, was supported by the National Institutes of Health. “The ability to flexibly learn in new […]
February 26, 2021

NIH study: people with SARS-CoV-2 antibodies may have a low risk of future infection

People who have had evidence of a prior infection with SARS-CoV-2, the virus that causes COVID-19, appear to be well protected against being reinfected with the virus, at least for a few months, according to a newly published study from the National Cancer Institute (NCI). This finding may explain why reinfection appears […]