2021

Researchers at Case Western Reserve University and partners in the United States and India are applying the investigative and predictive capabilities of artificial intelligence (AI) to help physicians customize treatments for patients with oral squamous cell carcinomas. Research shows that oral squamous cell carcinomas cancer is already the eighth-most common […]

Brown fat is that magical tissue that you would want more of. Unlike white fat, which stores calories, brown fat burns energy and scientists hope it may hold the key to new obesity treatments. But it has long been unclear whether people with ample brown fat truly enjoy better health. […]

Although some artificial intelligence software tested reasonably well, only one met the performance of human screeners, researchers found. Diabetes continues to be the leading cause of new cases of blindness among adults in the United States. But the current shortage of eye-care providers would make it impossible to keep up with the demand […]

Scientists at the University of California, Irvine have developed a new deep-learning framework that predicts gene regulation at the single-cell level. Deep learning, a family of machine-learning methods based on artificial neural networks, has revolutionized applications such as image interpretation, natural language processing and autonomous driving. In a study published […]

The microbiome comprises trillions of microorganisms living on and inside each of us. Historically, some researchers have guessed at its role in human health, but in the last decade or so genetic sequencing techniques have illuminated this galaxy of microorganisms enough to study it in detail. As researchers unravel the […]

Michael Green, M.D., PhD, noticed that when his patients had cancer that spread to the liver, they fared poorly – more so than when cancer spread to other parts of the body. Not only that, but transformative immunotherapy treatments had little impact for this patient. Uncovering the reason and a […]

Researchers at Oregon State University have found that a few organisms in the gut microbiome play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease affecting roughly one in 10 Americans. “Type 2 diabetes is in fact a global pandemic […]

The simple act of breathing is among the most familiar ways we convert nutrients to energy – inhaling molecules of oxygen and harmlessly breathing out unwanted material. But when our usual disposal mechanisms fail, the accumulated electrons can produce the kind of toxic event that causes many diseases, including cancer. […]

High blood pressure appears to accelerate a decline in cognitive performance in middle-aged and older adults, according to new research published today in Hypertension, an American Heart Association journal. Nearly half of American adults have high blood pressure or hypertension. Having high blood pressure is a risk factor for cognitive […]

A Washington state woman is recovering after a landmark organ transplant that she hopes will end her nearly decade-long bout with cancer. Kris Anderson, 51, of Redmond, received a lobe of liver from her daughter Lauren, 26, on Dec. 8. It was the Pacific Northwest’s first living-donor liver transplant for metastatic colorectal […]

Resveratrol and derived molecules were for a time excessively hyped as a means to trigger some of the beneficial metabolic response produced by calorie restriction, by acting on sirtuins, and thus have a positive impact on aging. The company Sirtris was founded to develop this area of research into a […]

Senolytic drugs are those capable of selectively destroying senescent cells. A range of such therapies are at various stages of development, including those that have reached initial human clinical trials. Senescent cell accumulation is an important cause of degenerative aging, and the removal of such cells via senolytic treatments has […]