2021

Hyaluronic acid (HA) is more than a buzzword ingredient touted by skincare brands. The “workhorse” capabilities of this biopolymer, which is present in most mammalian tissues, have fascinated scientists for decades. A new cover story in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, details HA’s complex […]

A study involving researchers at Karolinska Institutet and Gothenburg University has found that low levels of a protein called PDGFRb are associated with particularly good results of radiotherapy in women with early-stage breast cancer. The study, which is published in the journal Clinical Cancer Research, also suggests that the efficacy […]

Older people with kidney disease have a higher risk of dementia, and the risk increases with the rate and stage of kidney function decline. That is according to a large observational study by researchers at Karolinska Institutet in Sweden, published in the journal Neurology. The findings stress the significance of […]

Researchers have mapped the gene activity of osteocytes to improve their understanding of skeletal disease. Research led by the Garvan Institute of Medical Research has for the first time mapped the unique genetic profile of the skeleton’s ‘master regulator’ cells, known as osteocytes. The study published in Nature Communications outlines the […]

Determining safe yet effective drug dosages for children is an ongoing challenge for pharmaceutical companies and medical doctors alike. A new drug is usually first tested on adults, and results from these trials are used to select doses for pediatric trials. The underlying assumption is typical that children are like […]

For all animals, eliminating some cells is a necessary part of embryonic development. Living cells are also naturally sloughed off in mature tissues; for example, the lining of the intestine turns over every few days. One way that organisms get rid of unneeded cells is through a process called extrusion, […]

A new study from scientists at The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin reveals important findings, indicating that being overweight or obese significantly reduces blood flow in the brain. The study also shows that increased physical activity can positively modify, or even negate, this reduction in […]

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease. The findings were published online […]

People who have experienced a cerebral hemorrhage or brain bleed have a two-fold increase in the risk of having an ischemic stroke (caused by an artery blockage) or heart attack, compared with members of the general population, according to new research from investigators at Weill Cornell Medicine and NewYork-Presbyterian. The […]

COVID-19 pandemic has put us on our toes. It feels like it’s been bothering us for a very long time and the end is not in sight yet. However, vaccines may end this pandemic rather soon if we are efficient at vaccinating people. Now scientists from UCL say that it […]

University of Bristol research into octopus vision has led to a quick and easy test that helps optometrists identify people who are at greater risk of macular degeneration, the leading cause of incurable sight loss. The basis for this breakthrough was published in the latest issue of the Journal of Experimental […]

Cancer of the colon and rectum is one of the deadliest forms of cancer and has in recent years affected growing numbers of young people. In the largest registry study to date, researchers at Karolinska Institutet and Harvard University in the USA demonstrate a possible connection between colorectal polyps in […]