2021

Resilience, meaning the ability to recover from wounds, infection, and other forms of damage, is more or less the flip side of frailty in aging. Frailty increases, resilience decreases. A damaged system is less robustly resilient to further damage, as reliability theory tells us. Degenerative aging is precisely an accumulation […]

The body’s immune system is the first line of defence against infections like bacteria, viruses or cancers. Some cancers, however, have developed the art of molecular deception to avoid destruction by the body’s immune system. However, a University of Missouri researcher might have found a new way to help the […]

When kidneys are removed from deceased organ donors in the United States, they are often subjected to “procurement biopsies” and are discarded if certain abnormalities are seen in the kidney tissue — a practice that worsens the already-severe shortage of transplant-eligible kidneys in the country. However, a large portion of […]

The use of cannabidiol (CBD), the major non-psychoactive compound in cannabis, is on the rise across the United States. Pregnant women, in particular, may view CBD as more “natural” than other remedies for concerns such as nausea and pain, but the consequences of use for the developing fetus are unknown. […]

Exercise is known to improve health and extend the healthy portion of life span, but not extend life span itself in mice. This is a much lesser effect than that of calorie restriction, which does extend maximum life span in addition to improving health. From a very high level view, […]

Cancer is one of the world’s greatest health afflictions because, unlike some diseases, it is a moving target, constantly evolving to evade and resist treatment. In a paper published in an online issue of Nature, researchers at University of California San Diego School of Medicine and the UC San Diego […]

Touted by makers as a “healthy” alternative to traditional nicotine cigarettes, new research indicates the chemicals found in e-cigarettes disrupt the gut barrier and trigger inflammation in the body, potentially leading to a variety of health concerns. In the study, published in the journal iScience, Soumita Das, PhD, associate professor […]

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites — small molecules produced by the process of metabolism — may be predictive indicators for persons at risk for recurrent major depressive disorder. The findings were published in an online […]

Mutations that occur in certain DNA regions, called tandem repeats, may play a significant role in autism spectrum disorders, according to research led by Melissa Gymrek, assistant professor in the UC San Diego Department of Computer Science and Engineering and School of Medicine. The study, which was published in Nature, […]

Apollomics, Inc., an innovative biopharmaceutical company committed to the discovery and development of mono- and combination- oncology therapies, and GlycoMimetics (Nasdaq: GLYC), announced APL-106 (uproleselan) has been granted Breakthrough Therapy Designation (BTD) from the China National Medical Products Administration (NMPA) Center for Drug Evaluation (CDE) for the treatment of relapsed/refractory […]

Almost 18,000 Americans experience traumatic spinal cord injuries every year. Many of these people are unable to use their hands and arms and can't do everyday tasks such as eating, grooming or drinking water without help. In a small study of physical therapy combined with a non-invasive method of stimulating spinal-cord nerve […]

University of Alberta researchers have found an answer to a fundamental question in genomic biology that has eluded scientists since the discovery of DNA: Within the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid? In a study published in the […]