March 18, 2021

Nanotechnology could enable test for early Alzheimer’s Disease

University of Manchester scientists have discovered previously unseen blood biomarkers which could one day be used to test for Alzheimer’s disease, years before its symptoms appear. The ground-breaking study, published in ACS Nano, used cutting-edge nanotechnology uniquely developed and patented by the Nanomedicine Lab in Manchester, to extract blood signals of […]
March 18, 2021

Study: One enzyme dictates cells’ response to a probable carcinogen

In the past few years, several medications have been found to be contaminated with NDMA, a probable carcinogen. This chemical, which has also been found at Superfund sites and in some cases has spread to drinking water supplies, causes DNA damage that can lead to cancer. MIT researchers have now […]
March 18, 2021

Immune Receptor Protein Could Hold Key to Treatment of Autoimmune Diseases

TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models. They found that TARM1 activated dendritic cells, and the development of […]
March 18, 2021

Cancer patients set to benefit from £3.5m funding for cell therapies

CytoSeek’s technology is designed to help target the immune cells to the solid tumour and improve their cancer cell-killing ability. Solid tumours account for the majority of deaths from cancer and are notoriously difficult to treat, even with existing immune cell therapies, because the tumour suppresses immune cells’ ability to […]
March 18, 2021

How sperm remember

It has long been understood that a parent’s DNA is the principal determinant of health and disease in offspring. Yet inheritance via DNA is only part of the story; a father’s lifestyle such as diet, being overweight and stress levels have been linked to health consequences for his offspring. This […]
March 18, 2021

More precise diagnoses made possible with whole genome sequencing

More than 1,200 people with rare diseases have received a diagnosis thanks to the integration of large-scale genomics into the Stockholm region’s healthcare system. This is according to a study from Karolinska Institutet in Sweden that analysed the result of the first five years of collaboration on whole-genome sequencing between […]
March 18, 2021

Escape Artist

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity—such as individuals receiving immune-suppressive drugs for autoimmune diseases—can become chronically infected. As a result, their weakened immune defenses continue to attack the virus without being able to eradicate it fully. This physiological tug-of-war between […]
March 17, 2021

Supercomputing the secrets of the inner ear

The ears don't just help you hear. They also help a person walk, stand, and stay balanced. In fact, they work together with other systems in the body to help one understand our place in space. Many people who have sensations of vertigo find that the problem lies in their […]
March 17, 2021

Stem cell scientists start a buzz around fruit flies in hearing research

Even though a fruit fly doesn’t have ears, it can hear with its antennae. In a study published in the journal Development, USC Stem Cell scientists describe how adult flies can regenerate sensory hearing cells in their antennae, and how studying flies can provide a new way to understand and […]
March 17, 2021

Supercomputers Help Accelerate Alzheimer’s Research

Since 2009, Daniel Tward and his collaborators have analyzed more than 47,000 images of human brains via MRI Cloud—a gateway created to collect and share quantitative information from human brain images, including subtle changes in shape and cortical thickness. The latter was the topic of a recently published study in the […]
March 17, 2021

How to Speed Up Muscle Repair

A study led by researchers at the University of California San Diego Jacobs School of Engineering provides new insights for developing therapies for muscle disease, injury and atrophy. By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be […]
March 17, 2021

Researchers link breast cancer and bone growth

Breast cancer poses a substantial threat as it spreads to other organs, often lying in wait for years in these tissues and recurring without warning. Bones are a prime target, but the mechanisms that influence whether skeletal metastasis will develop or not remain poorly understood. A collaboration between researchers at […]