2021

Most cancer treatments produce a lot of senescent cells in the course of killing cancerous cells. This is thought to be the primary reason as to why cancer survivors have a reduced life expectancy and greater burden of age-related disease. Senescent cells secrete disruptive, inflammatory signals that harm tissue function […]

It is indisputably the case that regular exercise and maintenance of physical fitness into later life lowers the incidence and slows the progression of neurodegenerative disease. One can write any number of reviews akin to today's open access paper, walking through the evidence for cellular pathways involved in neurodegeneration to […]

Biochemistry is complex, and particularly so in the brain. The amyloid cascade hypothesis of Alzheimer's disease essentially states that slow aggregation of amyloid-β over years causes the onset of later and much more severe stages of Alzheimer's disease, meaning the chronic inflammation in brain tissue and tau aggregation that kills […]