February 2, 2021

The underestimated mutation potential of retrogenes

A new study from scientists of the Max Planck Institute for Evolutionary Biology in Plön, Germany, and the Chinese Academy of Sciences in Beijing shows that the potential genetic burden of mutations arising from retrogenes is significantly greater than originally thought. Genetic information is stored in DNA and transcribed as […]
February 2, 2021

Suppression of Tyrosine Degradation Modestly Extends Life Span in Flies

There are a great many ways to influence cellular metabolism to modestly slow the pace of aging, but few of them are of lll that much interest from a practical point of view, as a basis for therapies that might meaningfully extend human life spans. If an approach involves improvements […]
February 2, 2021

Faster tracking of treatment responses

Biological sensors developed by MIT spinout Glympse Bio could help clinicians make decisions for individual patients. In the fight against severe diseases like cancer, patients often endure a discomforting, weekslong gap between when treatment begins and when doctors can tell if it’s working. The problem often stems from an inability […]
February 2, 2021

Deep Vision: Near-Infrared Imaging and Machine Learning Can Identify Hidden Tumors

Near-infrared hyperspectral imaging combined with machine learning can visualize tumors in deep tissue and covered by a mucosal layer, scientists show Gastrointestinal stromal tumors are tumors of the digestive tract that grow underneath the mucus layer covering our organs. Because they are deep inside the tissue, these “submucosal tumors” are […]
February 2, 2021

Unusual mutation causes defective sperm in boars

ETH researchers have found a gene mutation that causes the sperm of boars to immobilize. Their discovery will help pig breeders to exclude animals with this genetic defect from breeding in future. In pig farming, natural mating between a boar and a sow has become rare. It is much more […]
February 2, 2021

Study offers hope of new treatment for accelerated aging in children

Researchers from Karolinska Institutet and Gothenburg University have investigated a potential new drug target for the rare genetic disorder Hutchinson-Gilford progeria syndrome that causes accelerated aging in children. The findings in mice are published in the scientific journal eLife and may aid in the development of more effective treatments for […]
February 2, 2021

New technology allows 3D printing bone tissue directly in patients' bodies

3D printing is the way of the future. Someday our houses may be 3D printed. 3D printers are already used in medicine as well, mostly to print tailored implants. Now scientists at UNSW Sydney have developed a new ceramic-based ink, which enables 3D printing of bone parts complete with the […]
February 2, 2021

Pregnant Mothers’ Antibodies to SARS-CoV-2 Transfer Efficiently to their Fetuses

Findings hint that vaccination of pregnant women might also protect their newborns. Antibodies to the SARS-CoV-2 coronavirus in the blood of pregnant women cross the placenta efficiently and are were found at similar concentrations in the blood of their newborns, according to a large study from researchers at the Perelman […]
February 2, 2021

Researchers develop injection to treat skin cancer

Yale researchers are developing a skin cancer treatment that involves injecting nanoparticles into the tumour, killing cancer cells with a two-pronged approach, as a potential alternative to surgery. The results are published in the Proceedings of the National Academy of Sciences. “For a lot of patients, treating skin cancer is […]
February 2, 2021

Trans-institutional collaboration receives $2 million BRAIN Initiative grant, developing brain organoids to map neurological development

Vivian Gama, assistant professor of cell and developmental biology, and Leon Bellan, associate professor of mechanical engineering and biomedical engineering, have won a $2.3 million, three-year grant from the National Institutes of Health Brain Research through Advancing Innovative Neurotechnologies Initiative.  The researchers will be developing three-dimensional brain organoids and related tissue—miniaturized and simplified versions produced in vitro—that resemble a human brain at 24 to 25 weeks post-conception. These will provide an unparalleled window […]