February 18, 2021

Middle-aged people with diabetes are facing a greater risk of COVID-19 death

As COVID-19 vaccines are rolling out, governments around the world are thinking about the most effective vaccination strategies. Who should get the vaccine first in order for the society to enjoy the greatest improvements in COVID-19 stats? Scientists at UCL say that one group might be overlooked – middle-aged people […]
February 18, 2021

Researchers eavesdrop on cellular conversations

New computational tool decodes biological language of signaling molecules. An interdisciplinary team of biologists and mathematicians at the University of California, Irvine have developed a new tool to help decipher the language cells use to communicate with one another. In a paper published in Nature Communications, the researchers introduce CellChat, […]
February 17, 2021

Combination treatment for common glioma type shows promise in mice

Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health, researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas — a type of slow-growing glioma—and […]
February 17, 2021

Preventing pressure injuries

Pressure injuries, also known as bedsores, are often understood as merely painful or uncomfortable side effects of immobility or limited mobility from a spinal cord injury or other causes. But they can also be deadly: At least 60,000 people die from pressure ulcers each year in the United States, according to […]
February 17, 2021

Immune therapies for heart disease aim of international research network

When a patient arrives in the emergency room with symptoms of a heart attack, doctors’ first priority is to restore blood flow to the heart muscle. Over the past few decades, therapeutic advances aimed at getting blood flowing and reducing strain on the heart have improved patients’ chances of surviving […]
February 17, 2021

Cystic Fibrosis and COVID-19

People with cystic fibrosis, or CF, don’t appear to be especially susceptible to COVID-19, and when they do get infected, they don’t seem to get sicker, based on clinical data so far. But Ruobing (Ruby) Wang, an assistant professor of paediatrics at Harvard Medical School who cares for patients with CF […]
February 17, 2021

Adversity in Childhood May Lead to Early Aging for Women

Women who have experienced high levels of trauma in childhood, such as abuse by a parent, are biologically older at the epigenetic cellular level in adulthood than women of the same age who have not experienced such adversity, according to a new study by UC San Francisco. Epigenetic “clocks” measure […]
February 17, 2021

‘AutoImmunoprofiler’ Builds on Success in Cancer Research to Advance Treatments for Autoimmune Diseases

UC San Francisco scientists have formed a research alliance with pharmaceutical firm Eli Lilly and Company aimed at better understanding autoimmune diseases and fostering the development of new therapies. Based on the innovative Immunoprofiler model launched at UCSF in 2015, the new initiative, called AutoImmunoprofiler, inherits the most successful aspects of […]
February 17, 2021

3D images provide important knowledge about brain health

The brain is involved in everything in our body. When so-called neurodegenerative diseases such as Alzheimer's, ALS and multiple sclerosis attack the brain, they gradually degrade the human ability to concentrate, speak, remember and move. Despite extensive research, there is much that we still do not know about the brain. […]
February 17, 2021

Study Finds Alligator Hearts Keep Beating No Matter What

Mammals and cold-blooded alligators share a common four-chamber heart structure – unique among reptiles – but that’s where the similarities end. Unlike humans and other mammals, whose hearts can fibrillate under stress, alligators have built-in antiarrhythmic protection. The findings from new research were reported in the journal Integrative Organismal Biology. […]
February 17, 2021

Fixer-upper: Understanding the DNA repair toolkit to chart cancer evolution

The relationship between DNA repair pathways and cancer cells can give scientists clues for identifying potential treatments The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search for […]