April 17, 2021

An ion pump to deliver chemotherapy agents to the brain

Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumours. Researchers at Linköping University, Sweden, and the Medical University of Graz, Austria, have shown in cells in culture that an ion pump can deliver drugs more accurately, which gives less severe […]
April 17, 2021

Processed meat linked to cardiovascular disease and death

A global study led by Hamilton scientists has found a link between eating processed meat and a higher risk of cardiovascular disease. The same study did not find the same link with unprocessed red meat or poultry. The information comes from the diets and health outcomes of 134,297 people from […]
April 17, 2021

Team unlocks possible Crohn’s disease trigger

Potentially game-changing research led by McMaster University scientists may finally bring relief to millions of people worldwide living with Crohn’s disease. Investigator Brian Coombes said his team identified a strain of adherent-invasive E-coli (AIEC) that is strongly implicated in the condition and is often found in the intestines of people […]
April 17, 2021

FSU College of Medicine research links Parkinson’s disease and neuroticism

New research from the Florida State University College of Medicine has found that the personality trait neuroticism is consistently associated with a higher risk of developing the brain disorder Parkinson’s disease. The research by Professor of Geriatrics Antonio Terracciano and team, published in Movement Disorders, found that adults in the study […]
April 17, 2021

New type of cell contributes to increased understanding of ALS

The causes of the serious muscle disease ALS still remain unknown. Now, researchers at Karolinska Institutet and KTH Royal Institute of Technology, among others, have examined a type of cell in the brain blood vessels that could explain the unpredictable disease origins and dynamics. The results indicate a hitherto unknown […]
April 16, 2021

7.2% of All Deaths Worldwide are Attributable to Physical Inactivity

Humans evolved in an environment of physical exertion, and our biochemistry requires physical exertion in order to trigger mechanisms of cell maintenance and metabolic regulation. Populations that exercise vigorously into late old age, such as the Tsimane in Bolivia, exhibit very much lower levels of cardiovascular disease. Further, living a […]
April 16, 2021

UO discovery could one day help rejuvenate the adult brain

Imagine a drug that could temporarily reenergize plasticity in the brain to treat autism or schizophrenia, or even help an adult’s ageing brain pick up a new language or learn to play a musical instrument. Such are the potential, down-the-road medical implications of a discovery made by a postdoctoral researcher […]
April 16, 2021

CD40 Drug Before Surgery Shows Promise in Early-stage Pancreatic Cancer

Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new study from researchers in the Abramson Cancer Center (ACC) at the University of Pennsylvania. Changing the microenvironment from so-called T cell […]
April 16, 2021

Power of light and oxygen clears Alzheimer’s disease protein in live mice

A small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the brains of Alzheimer’s disease patients. If perfected in humans, the technique could be used as an alternative approach to immunotherapy and used to treat other diseases caused by similar […]
April 16, 2021

TAU researchers achieve breakthrough in battle against brain cancer

Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer. TAU researchers have identified a failure in the brain’s immune system that leads to the amplification of cell division and the spread of glioblastoma cancer cells. The failure results partially from the secretion […]
April 16, 2021

Biomarker Could Help Identify Difficult-to-Diagnose Kidney Cancer Subtype

High expression levels of the gene TRIM63 can serve as an accurate and sensitive biomarker of a subtype of kidney cancer known as microphthalmia-associated transcription factor family aberration-associated renal cell carcinomas — or MiTF renal cell carcinoma. That’s according to a new, multi-institution study led by researchers at the University of Michigan Center for Translational […]
April 16, 2021

Does Public Policy Affect Alcohol-Related Liver Disease Deaths?

Alcohol-related liver disease is on the rise in the United States. Most strikingly, this epidemic is disproportionally affecting young, otherwise healthy, people, leading to rapid increases in alcohol-related liver disease deaths. “Changes in mortality rates for the alcohol-related liver disease vary significantly from state to state, so we think socioeconomic […]