General

UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation and reversed liver damage in mice — even while the animals remained on an unhealthy diet. The […]

A new study has found that diet, gut health, cardiovascular conditions and surgical history are some of the strongest predictors of Alzheimer’s risk, which could lead to better screening and prevention through simple lifestyle changes. Alzheimer's disease affects more than 55 million people worldwide, and that number is projected to […]

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human brain development before birth — a resource that resolves longstanding contradictions in the field and could lay the groundwork for future therapeutic strategies. The study, published in Science, analyzed more than 100,000 nuclei […]

For roughly forty years, oncologists have treated pancreatic cancer with the grim arithmetic of months gained, not years. A new drug called daraxonrasib appears ready to rewrite that math. In late-stage trial data, patients who added it to chemotherapy lived roughly twice as long as those on chemo alone – […]

Learning a new language or relearning speech after a stroke requires coordinated movements that are controlled by networks in the brain. This includes the orofacial sensory system (input such as touch and position from the lips, tongue, jaw, and face) and the motor system (commands that move the muscles in […]

Researchers have created a detailed map of a deadly childhood cancer, showing it uses ‘shields’ and ‘bodyguards’ to protect itself, paving the way for new treatments. University of Queensland researchers used cutting-edge technology to map the biology of neuroblastoma – a cancer that typically develops in children under the age […]

Researchers from The University of Western Australia will use biomaterials to create a lifelike 3D model of human skin to better understand and treat skin stiffness associated with age, scarring and disease. If successful, in time the model could reduce the need for animal testing of skin products and enable […]

Cancer is often described as a genetic roll of the dice. A matter of bad luck. But new global estimates from the World Health Organization suggest something different: four in 10 cancer cases could be prevented worldwide. That statistic raises an obvious question: If so many cancers are preventable, what […]

Nanobodies — miniature proteins derived from camel antibodies — demonstrated powerful potential to accurately and safely deliver radioisotopes as specialized cancer treatments in a project at ORNL. The unusual antibodies were first observed in 1989 by Belgian researchers studying the immune system of camelids — animals such as camels, alpacas […]

Research published in Science Advances has uncovered new insights into why the most aggressive oesophageal cancers are so difficult to treat and how the body’s own defence systems are helping them to thrive. The study, led by Professor Eileen Parkes and her team in the Department of Oncology at the University of Oxford, analysed patient-donated tumour […]