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Nanobodies — miniature proteins derived from camel antibodies — demonstrated powerful potential to accurately and safely deliver radioisotopes as specialized cancer treatments in a project at ORNL. The unusual antibodies were first observed in 1989 by Belgian researchers studying the immune system of camelids — animals such as camels, alpacas […]

Research published in Science Advances has uncovered new insights into why the most aggressive oesophageal cancers are so difficult to treat and how the body’s own defence systems are helping them to thrive. The study, led by Professor Eileen Parkes and her team in the Department of Oncology at the University of Oxford, analysed patient-donated tumour […]

University of Queensland researchers who mapped cancer cell ‘neighbourhoods’ in the most common type of lung cancer have found cell metabolism plays a critical role in determining how lung cancer patients will respond to immunotherapy. Associate Professor Arutha Kulasinghe from UQ’s Frazer Institute said machine learning algorithms and computational approaches […]

Aging muscles heal more slowly after injury — a frustrating reality familiar to many older adults. A new UCLA study conducted in mice reveals an unexpected cause: Stem cells in aged muscle accumulate higher levels of a protein that slows their ability to activate and repair tissue, but helps the […]

The shingles vaccine was never meant to protect anyone's brain. It was built to stop a painful rash. But study after study now shows that people vaccinated against shingles face significantly lower dementia risk — and the latest research suggests those already-impressive numbers might be too conservative. A newer, more […]

The Manufacturing Bottleneck That Defines Cellular Therapy Economics The cellular therapy revolution faces a fundamental economic challenge: autologous manufacturing costs between $78,000 and $93,000 per patient before hospital administration begins, with facility costs alone comprising 51-56% of total production expenses. This isn't scalable manufacturing in the traditional pharmaceutical sense. It's […]

University of Queensland researchers say the discovery of a new stress reduction role for a naturally occurring molecule in the body could lead to new drugs and treatment for metabolic disorders and ageing. Professor Steven Zuryn, a molecular geneticist from UQ’s Queensland Brain Institute, was part of a team that […]

Researchers at the University of Southampton have developed a promising new way to bolster the body’s immune system response to cancer. In a study published in Nature Communications , researchers used specially engineered multi-pronged antibodies to better activate cancer-killing T cells. The antibodies work by ‘grabbing’ and ‘clustering’ multiple immune […]

Passive activities such as watching television have been linked to worse memory and cognitive skills, while ‘active sitting’ like playing cards or reading correlate with better brain health, researchers have found. Associate Professor Paul Gardiner from The University of Queensland’s School of Public Health said the findings could be used […]