General

University of Queensland researchers who mapped cancer cell ‘neighbourhoods’ in the most common type of lung cancer have found cell metabolism plays a critical role in determining how lung cancer patients will respond to immunotherapy. Associate Professor Arutha Kulasinghe from UQ’s Frazer Institute said machine learning algorithms and computational approaches […]

Aging muscles heal more slowly after injury — a frustrating reality familiar to many older adults. A new UCLA study conducted in mice reveals an unexpected cause: Stem cells in aged muscle accumulate higher levels of a protein that slows their ability to activate and repair tissue, but helps the […]

The shingles vaccine was never meant to protect anyone's brain. It was built to stop a painful rash. But study after study now shows that people vaccinated against shingles face significantly lower dementia risk — and the latest research suggests those already-impressive numbers might be too conservative. A newer, more […]

The Manufacturing Bottleneck That Defines Cellular Therapy Economics The cellular therapy revolution faces a fundamental economic challenge: autologous manufacturing costs between $78,000 and $93,000 per patient before hospital administration begins, with facility costs alone comprising 51-56% of total production expenses. This isn't scalable manufacturing in the traditional pharmaceutical sense. It's […]

University of Queensland researchers say the discovery of a new stress reduction role for a naturally occurring molecule in the body could lead to new drugs and treatment for metabolic disorders and ageing. Professor Steven Zuryn, a molecular geneticist from UQ’s Queensland Brain Institute, was part of a team that […]

Researchers at the University of Southampton have developed a promising new way to bolster the body’s immune system response to cancer. In a study published in Nature Communications , researchers used specially engineered multi-pronged antibodies to better activate cancer-killing T cells. The antibodies work by ‘grabbing’ and ‘clustering’ multiple immune […]

Passive activities such as watching television have been linked to worse memory and cognitive skills, while ‘active sitting’ like playing cards or reading correlate with better brain health, researchers have found. Associate Professor Paul Gardiner from The University of Queensland’s School of Public Health said the findings could be used […]

University of Queensland researchers have developed a promising new anti-inflammatory drug and, for the first time, used advanced imaging to watch its effects unfold inside the living brain, a breakthrough that could accelerate treatments for Parkinson’s disease. Lead author Dr Eduardo Albornoz Balmaceda from the School of Biomedical Sciences said […]

A customized mRNA vaccine designed to fight aggressive skin cancer has delivered sustained protection over five years. Patients receiving the experimental treatment alongside standard immunotherapy saw their risk of cancer returning or dying drop by nearly 50 percent compared to those on immunotherapy alone. Key Takeaways: Moderna and Merck released […]

A cancer-targeting antibody that helps the body’s immune cells spot and destroy hard-to-treat tumours such as triple-negative breast cancer has been developed by researchers. The University of Queensland’s Associate Professor Fernando Guimaraes said the antibody recognises a unique part of the ROR1 protein, which is found on many aggressive cancers […]

A large, multi-institution study led by a Brown University physician-scientist could have important implications for the development of new classes of cancer therapeutics. Interrupting one function of a protein that plays a key role in cell signaling could enable the development of new cancer treatments, according to a study led […]

Patients who discontinue weight-loss medications see their progress vanish quickly, with comprehensive research revealing a concerning pattern of rapid reversal in both weight reduction and health improvements. Key Takeaways: Analysis of 9,341 patients across 37 studies examined outcomes from 18 different weight-loss medications. The data paints a clear picture: stopping […]

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University. The results may also explain why combining certain cancer drugs can produce the opposite of the intended effect. The […]