General

Written by Vytautas Valinskas Key takeaways Two results, one week apart, and very different evidence On 26 August the US Food and Drug Administration approved Rasonque, the brand name for daraxonrasib, for adults with metastatic pancreatic adenocarcinoma who have already had one systemic therapy or cannot take combination chemotherapy. One week […]

When a cell gets ready to divide, it shuts down its gene-reading machinery almost entirely. “As cells prepare to divide, they rapidly shut down most gene reading, or transcription,” says Claudio R. Alarcón, PhD, associate professor of pharmacology at Yale School of Medicine. “At that point, the cell needs to focus […]

USC researchers found that exposure to common air pollutants was associated with different patterns of cortical thickness in two groups of older adults, pointing to a potentially complex relationship between pollution, aging, and brain health. Exposure to common forms of outdoor air pollution may be linked to structural changes in […]

Cancer, arthritis, and diabetes can develop when cells activate the wrong genes. Yet, those failures are remarkably rare. Every second of every day, trillions of cells correctly respond to environmental stress, keeping our bodies functional.

For decades, the beauty and skincare industries operated under a relatively straightforward paradigm: identify a visible sign of ageing- be it a fine line, a dark spot, or sagging skin-and develop a topical solution to camouflage or temporarily correct it. This reactionary framework defined the traditional “anti-ageing” market. However, a […]

The technology that rushed COVID-19 vaccines to clinics in record time has found a second calling. mRNA-based treatments are now holding melanoma in check for years and showing early wins against pancreatic and brain tumors, cancers long thought untouchable by the immune system. Key Takeaways: The progress arrives at an […]

Hormonal changes during midlife can affect sleep, mood, energy levels, and overall well-being. For many women, these changes can feel confusing because symptoms often overlap with stress, lifestyle shifts, or normal aging. In recent years, hormone tracking technology has become more accessible and easier to use, helping women better understand […]

UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation and reversed liver damage in mice — even while the animals remained on an unhealthy diet. The […]