March 19, 2021

Cells burn more calories after just one bout of moderate aerobic exercise

In a recent study testing the effects of exercise on overall metabolism, researchers at Oregon State University found that even a single session of moderate aerobic exercise makes a difference in the cells of otherwise sedentary people. Mitochondria are the part of the cell responsible for the biological process of […]
March 19, 2021

Identifying Cells to Better Understand Healthy and Diseased Behavior

In researching the causes and potential treatments for degenerative conditions such as Alzheimer’s or Parkinson’s disease, neuroscientists frequently struggle to accurately identify cells needed to understand brain activity that gives rise to behaviour changes such as declining memory or impaired balance and tremors. A multidisciplinary team of the Georgia Institute […]
March 19, 2021

Double duty: Gut’s immune system helps regulate food processing, too

The small intestine is ground zero for survival of animals. It is responsible for absorbing the nutrients crucial to life and it wards off toxic chemicals and life-threatening bacteria. In a new study published in the journal Science, Yale researchers report the critical role played by the gut’s immune system […]
March 19, 2021

Mystery of four-stranded DNA begins to unravel

New insights into a little-understood DNA structure could provide the basis for new cancer therapies. DNA is usually depicted as double-stranded, but not much is known about parts of the genome that adopt four-stranded structures known as quadruplexes. UC Riverside researchers have discovered that they play a key role in […]
March 18, 2021

Age-Related Vision Impairment Correlates with Mortality

Researchers here note an association between vision impairment and mortality in later life. This has the look of a correlation that exists because aging is a global process at work throughout the body. It stems from the accumulation of a few classes of cell and tissue damage. That damage causes […]
March 18, 2021

Nanotechnology could enable test for early Alzheimer’s Disease

University of Manchester scientists have discovered previously unseen blood biomarkers which could one day be used to test for Alzheimer’s disease, years before its symptoms appear. The ground-breaking study, published in ACS Nano, used cutting-edge nanotechnology uniquely developed and patented by the Nanomedicine Lab in Manchester, to extract blood signals of […]
March 18, 2021

Study: One enzyme dictates cells’ response to a probable carcinogen

In the past few years, several medications have been found to be contaminated with NDMA, a probable carcinogen. This chemical, which has also been found at Superfund sites and in some cases has spread to drinking water supplies, causes DNA damage that can lead to cancer. MIT researchers have now […]
March 18, 2021

Immune Receptor Protein Could Hold Key to Treatment of Autoimmune Diseases

TARM1 is a receptor protein whose role in the functioning of the immune system is unknown. In a new study, scientists from Japan have explored the potential role of TARM1 in the pathogenesis of rheumatoid arthritis by analyzing mouse models. They found that TARM1 activated dendritic cells, and the development of […]
March 18, 2021

Cancer patients set to benefit from £3.5m funding for cell therapies

CytoSeek’s technology is designed to help target the immune cells to the solid tumour and improve their cancer cell-killing ability. Solid tumours account for the majority of deaths from cancer and are notoriously difficult to treat, even with existing immune cell therapies, because the tumour suppresses immune cells’ ability to […]
March 18, 2021

How sperm remember

It has long been understood that a parent’s DNA is the principal determinant of health and disease in offspring. Yet inheritance via DNA is only part of the story; a father’s lifestyle such as diet, being overweight and stress levels have been linked to health consequences for his offspring. This […]
March 18, 2021

More precise diagnoses made possible with whole genome sequencing

More than 1,200 people with rare diseases have received a diagnosis thanks to the integration of large-scale genomics into the Stockholm region’s healthcare system. This is according to a study from Karolinska Institutet in Sweden that analysed the result of the first five years of collaboration on whole-genome sequencing between […]
March 18, 2021

Escape Artist

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity—such as individuals receiving immune-suppressive drugs for autoimmune diseases—can become chronically infected. As a result, their weakened immune defenses continue to attack the virus without being able to eradicate it fully. This physiological tug-of-war between […]
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