General

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form—which tests positive for hormone receptors (HR+) and negative for the HER2 receptor—usually respond well to treatment. But for those in advanced stages, few treatment options existed until […]

When it comes to protecting the newborn brain, taking steps to mitigate risk before birth may be critical. Some newborns, such as those with intrauterine growth restriction (IUGR), are at heightened risk. Being able to intervene before birth to aid in protecting the newborn brain may prevent the often-devastating effects […]

You are just billions of different cells interacting between themselves in order to maintain this big beautiful organism that is you. Sometimes this includes cells committing suicide – they have to vacate their place for the benefit of others. The self-destruction of cells in humans and plants, however, is not […]

In The Wizard of Oz, the Tin Man famously sang, “If I only had a heart . . . “ Although the Tin Man had to be satisfied with a heart-shaped clock, researchers reporting in ACS’ Nano Letters have now created a miniature cyborg heart that produces electrical signals like the human version. […]

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic. In a paper published in Cancer Research, University of California San Diego School of Medicine researchers identified a new therapeutic approach in mouse models […]

Cells in the body proliferate at different rates. Some divide constantly and throughout life, like the ones that line the gut. Others divide only rarely, sometimes resting for several years in a non-dividing state. Now, a study led by scientists at MIT's Whitehead Institute sheds light on the molecular mechanisms […]

MIT biologists have discovered an unexpected effect of a ketogenic, or fat-rich, diet: They showed that high levels of ketone bodies, molecules produced by the breakdown of fat, help the intestine to maintain a large pool of adult stem cells, which are crucial for keeping the intestinal lining healthy. The […]

Cytokines are a type of proteins that are important to the signaling between cells in the body's immune system, for example in the case of an infection or injury. A new study in the Journal of Allergy and Clinical Immunology, by researchers at Karolinska Institutet and Lund University, is now […]

Fat-soluble statins can prevent liver cancer and reduce mortality in patients with chronic viral hepatitis. These are findings from a study conducted by researchers at Karolinska Institutet in Sweden, among others. The study is published in Annals of Internal Medicine. Chronic viral hepatitis (hepatitis B and C) are severe conditions […]

It’s well established that chronic inflammation can lead to colon cancer, but the molecular mechanisms behind this association aren’t fully understood. Research at Vanderbilt University Medical Center into the role that the signaling protein SMAD4 plays in this process has received funding from the National Cancer Institute. The co-principal investigators […]

Vitamin D deficiency in middle childhood could result in aggressive behavior as well as anxious and depressive moods during adolescence, according to a new University of Michigan study of school children in Bogotá, Colombia. Children with blood vitamin D levels suggestive of deficiency were almost twice as likely to develop […]

As you age your blood pressure is likely to change. That is a normal part of life, which is predictable and can be easily addressed with our current medication. Blood pressure is not to be taken lightly, because it is a major indicator of cardiovascular health. Now a UCL-led research […]