General

Even if we don’t think about it this way, we are still just a bunch of animals. We are mammals, connected to the laws of nature as tightly as the next species. And so our lives are divided into biological periods, which for women include menopause. However, for some women […]

Creating an effective gene therapy for inherited diseases requires three key steps. First, scientists must identify and characterize the disease. Second, they must find the gene responsible. And finally, they must find a way to correct the impairment. Four years ago, a team from the University of Pennsylvania, in collaboration with […]

Distinct patterns of electrical activity in the sleeping brain may influence whether we remember or forget what we learned the previous day, according to a new study by UC San Francisco researchers. The scientists were able to influence how well rats learned a new skill by tweaking these brainwaves while […]

Two new studies by an international team of researchers report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease (PMD), a rare genetic condition affecting boys that can be fatal before 10 years of age. Often diagnosed at birth with symptoms of weakness and breathing difficulties, the […]

A new 3D structure for growing cell cultures could enable doctors to test medications on model tumors grown from a patient’s own cells, according to results from a team of engineers and cancer researchers at the University of Michigan. Unlike previous devices, the new structure is made from protein fibers […]

Researchers at the National Institutes of Health have developed a new and improved viral vector—a virus-based vehicle that delivers therapeutic genes—for use in gene therapy for sickle cell disease. In advanced lab tests using animal models, the new vector was up to 10 times more efficient at incorporating corrective genes […]

In a virtual world, a knight in full armour sits in front of me, expectantly waiting for me to deal them some playing cards. As the game progresses, a large black spot grows in the middle of my vision. I try to pick up the deck of cards from the […]

There is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherapy is still the most widely used cancer treatment, but chemotherapy attacks all the rapidly dividing cells that it locates within the body, whether they're ultimately harmful or beneficial. A […]

It may sound odd, but most tests for hereditary cancer risks are prescribed by doctors after the patient has been diagnosed with cancer – past the time when such information would be prospectively most useful to the patient. With that backdrop, UW Medicine researchers will explore the feasibility and benefits of administering […]

A biochemist at the University of California, Riverside, has received a grant from the Congressionally Directed Medical Research Programs, or CDMRP, of the U.S. Department of Defense to develop a novel lead compound to treat breast cancer, the second most commonly diagnosed cancer among American women. John Jefferson Perry, an assistant professor […]

The National Institute on Aging (NIA) is awarding approximately $37 million over five years to a team of international researchers, led by Emory University, to help accelerate the development of promising new therapies that will effectively treat or prevent Alzheimer’s disease (AD). NIA is part of the National Institutes of […]

People with heart disease or defective or artificial heart valves are at increased risk of developing a potentially deadly valve infection. Rutgers researchers reported that new risk factors for this condition have emerged and that an increasing number of patients admitted to hospitals for other diseases are at risk of […]