General

A ‘biobank’ of pancreatic tumour samples, administered by the Garvan Institute of Medical Research, has contributed to the most comprehensive database of cancer genomes in the world to date. The Australian Pancreatic Cancer Genome Initiative (APGI) contributed 175 genomes to the Pan-Cancer Project, a global effort that has created a resource […]

Genetically-edited immune cells can persist, thrive, and function months after a cancer patient receives them, according to new data published by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn’s Abramson Cancer Center. The team showed cells removed from patients and brought back into the lab setting were […]

In a new study, researchers from DTU and the research unit for childhood asthma COPSAC have—as the first in the world—showing that immune system responses in children as young as 18 months can be used to predict the risk of them developing intermittent or persistent asthma. The method used by […]

How do some mammals postpone the development of their embryos to await better conditions for having offspring?  A recent study at the UW Medicine Institute for Stem Cell and Regenerative Medicine explored this reproductive enigma, which can occur in more than 130 species of mammals as well as in some […]

An elaborate system of filaments, liquid droplet dynamics and protein connectors enables the repair of some damaged DNA in the nuclei of cells, researchers at the University of Toronto have found. The findings further challenge the belief that broken DNA floats aimlessly – and highlight the value of cross-disciplinary research […]

From plastics to pesticides, it seems like every week delivers fresh news about the dangers of endocrine disruptors—chemicals in the environment that alter the body’s hormones and can lead to reproductive, developmental, neurologic and immune problems and cancer. Industry regulation and individual consumer choice can reduce exposure to such chemicals, […]

Loud noise can damage the inner ear and cause hearing loss. Studying mice, researchers at Washington University School of Medicine in St. Louis and the University of Iowa have shown that a drug compound can block damage caused by loud noise, raising the possibility of medication that prevents noise-induced hearing […]

Dementia is one of the most debilitating consequences of Parkinson’s disease, a progressive neurological condition characterized by tremors, stiffness, slow movement and impaired balance. Eighty percent of people with Parkinson’s develop dementia within 20 years of the diagnosis, and patients who carry a particular variant of the gene APOE are at especially […]

Clumps of proteins inside cells are a common thread in many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) or Lou Gehrig’s disease. These clumps, or solid aggregates of proteins, appear to be the result of an abnormality in the process known as liquid-liquid phase separation (LLPS), in which individual proteins […]

From avoiding lower back pain to burning more calories and improving memory, weightlifting offers wide-ranging benefits for body and mind, say U of A experts. While research shows little or no link between exercise and any meaningful long-term weight loss, that doesn’t mean exercising, particularly resistance training, doesn’t provide a […]

Biologists identify hearing-loss receptor in mice, use drug to prevent hearing damage. Once you start to lose your hearing, you can’t get it back. But what if you could prevent hearing loss by blocking in advance the effects of loud noises? That’s a route a team of biologists at the University […]

Survival may more than double for adults with glioblastoma, the most common and deadly type of brain tumor, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor. This discovery, reported in a retrospective study headed by researchers at UC San Francisco, is […]