General

Scientists are making important progress in the battle against a class of devilishly complex human pediatric brain cancers thanks to a new study from a team of Florida State University students and faculty. Among young children, there’s no brain tumor more common than medulloblastoma. But no specific and effective therapy […]

The human body's immune system is like a vast team of special agents. Certain cells called T cells each individually specialize in recognizing a particular intruder, such as the influenza virus or salmonella. Determining a given T cell's target is a critical step in designing personalized treatments for cancers and […]

For children undergoing immunotherapy – a promising treatment for peanut allergies – uncomfortable side effects can induce anxiety, perhaps to the point of skipping doses or dropping treatment entirely. But guiding young patients to the mindset that uncomfortable side effects are a sign that treatment is working can help reduce […]

The team, at the University’s European Cancer Stem Cell Research Institute, found they could stop gastric cells dividing and growing by deleting a particular cell-surface receptor implicated in the function of stem cells. Dr Toby Phesse, Cardiff University, said: “The prognosis of gastric cancer is very poor, with very few […]

Hypertrophic cardiomyopathy (HCM) is the most common genetic disease of the heart and a leading cause of sudden cardiac death in young people and athletes.Scientists have long known that the condition’s cardinal feature—an unusually thick heart muscle that contracts and relaxes abnormally—is fueled by some glitch in the heart’s molecular machinery. Yet, the spark-plug that […]

Harvard Medical School geneticists have created a new model-in-a-dish of sporadic Alzheimer’s disease, which accounts for more than 90 percent of Alzheimer’s cases and tends to strike people without a family history of the disease. The model marks the first time researchers have identified the same molecular abnormalities across multiple […]

In a first-of-its-kind study, scientists at the University of Missouri have helped advance a patient-specific, precision medicine treatment for bone cancer in dogs. By creating a vaccine from a dog’s own tumor, scientists worked with ELIAS Animal Health to target specific cancer cells and avoid the toxic side effects of chemotherapy, while […]

The natural world, with all its diversity, is a popular place for researchers to go looking for new drugs, including those that fight cancer. But there is often a wide gap between finding a plant, sponge, or bacterium that contains a candidate drug, and actually bringing a medicine to the […]

Leukaemia promotes premature ageing in healthy bone marrow cells – according to new research from the University of East Anglia. Findings published today in the journal Blood show that healthy bone marrow cells were prematurely aged by cancer cells around them. It is well known that ageing promotes cancer development. […]

The INTERGROWTH-21st Project, funded by the Bill & Melinda Gates Foundation and led by the University of Oxford’s Nuffield Department of Women’s & Reproductive Health, has already shown that healthy, well-nourished women, free of disease, living in a clean environment and receiving good antenatal care have children with similar skeletal […]

The causes of autism spectrum disorder (ASD) are diverse and to some extent, unknown. But without doubt, they are complex, layered and deeply nuanced. In a study published in Translational Psychiatry, researchers at University of California San Diego School of Medicine describe how, in a novel mouse model, epigenetic regulation negatively […]

An 18-month federally-sponsored project led by the Georgia Institute of Technology will develop much-needed curriculum to train workers for the fledgling cell manufacturing industry. Research teams at the University of Georgia (UGA) and the University of Pennsylvania (UPenn), along with four private firms, are also taking part in the $1.4 […]