October 26, 2020

Melanoma research brings understanding of cellular resistance to cancer treatment, opening doors to new cures

A Vanderbilt cancer systems biology team has identified the enzymes that keep tumor cells growing in the presence of drug treatment, opening the door to stopping these cells dead in their tracks. An article, “An Integrative Gene Expression and Mathematical Flux-Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells,” was published […]
October 26, 2020

A New Tool for the Genomic Era

As early as 1975, biologists discovered that the protein-coding parts of the chimpanzee and human genomes are more than 99 percent identical. Yet, chimpanzees and humans are clearly different in significant ways. Why? The answer lies in the fact that how DNA is used is as important as what it […]
October 26, 2020

Toward a New Staging System for Prostate Cancer, and Why it Matters

Doctors and biostatisticians at the University of Michigan Rogel Cancer Center have led the development and validation of a staging system to better predict outcomes and inform treatment decisions for men diagnosed with non-metastatic prostate cancer. Although it is one of the most common cancers worldwide, prostate cancer remains one of the […]
October 26, 2020

Researchers discover molecular link between diet and risk of colorectal cancer

An international team of researchers has identified a direct molecular link between meat and dairy diets and the development of antibodies in the blood that increase the chances of developing cancer. This connection may explain the high incidence of cancer among those who consume large amounts of dairy products and […]
October 26, 2020

How cells use mechanical tension sensors to interact with their environment

Actin is among the most abundant proteins in cells, and it has many jobs—from giving the cell its very shape and structure to managing networks of proteins crucial to numerous cellular functions. Without it, the fragile fundamental unit of life would crumble. A good deal of actin’s activity is based […]
October 26, 2020

Vaccines and rare diseases

Imagine your young son has a rare disease that makes him susceptible to infections. If he catches the measles, will he be able to successfully fight it off? A researcher at Université de Montréal has discovered how to ensure he will: by getting him vaccinated. For people generally, vaccination is […]
October 26, 2020

Researchers show why heat stress damages sperm

University of Oregon biologists have used a model organism to identify molecular mechanisms that produce DNA damage in sperm and contribute to male infertility following exposure to heat. In humans, the optimal temperature for sperm production is just below body temperature, in a range of about 90-95 degrees F. Human […]
October 26, 2020

SPOTlight supercharges cell studies

Researchers at Rice University and Baylor College of Medicine have developed a new method to isolate specific cells, and in the process found a more robust fluorescent protein. Both the platform and the protein could be highly useful to synthetic biologists and biomedical researchers. They often need to single out […]
October 26, 2020

NIH awards over $100 million to examine biomarkers of Alzheimer’s disease in adults with Down syndrome

The Alzheimer’s Biomarkers Consortium – Down Syndrome (ABC-DS), a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health (NIH), to expand research on the biomarkers of Alzheimer’s disease in adults with Down syndrome. UCI principal investigators Elizabeth […]
October 25, 2020

Researchers discover mechanism linking gum disease to heart disease, other conditions

Researchers at the University of Toronto have found evidence that neutrophil immune cell activity is the missing link connecting periodontal disease with heart disease, cancer and other inflammatory conditions – possibly including COVID-19. The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, […]
October 25, 2020

Humans are born with brains ‘prewired’ to see words

Humans are born with a part of the brain that is prewired to be receptive to seeing words and letters, setting the stage at birth for people to learn how to read, a new study suggests. Analyzing brain scans of newborns, researchers found that this part of the brain – […]
October 25, 2020

Newly discovered mechanism controls cancer cell growth and metabolism

In a new study published in the journal Cell, Death & Differentiation researchers at Karolinska Institutet have conducted a translational study that identified a new mechanism for controlling the breakdown of glucose in several different cancer forms. The discovery could lead to new therapeutic strategies aimed to reduce cancer growth. […]
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