January 25, 2021

Catching cancer in the act

When cancer is confined to one spot in the body, doctors can often treat it with surgery or other therapies. Much of the mortality associated with cancer, however, is due to its tendency to metastasize, sending out seeds of itself that may take root throughout the body. The exact moment […]
January 22, 2021

‘Junk DNA’ plays a key role in regulating circadian clocks

If you’ve ever had a bad case of jet lag, you know how a disruption to your body’s circadian rhythm makes it difficult to function. Molecular circadian “clocks” exist in cells throughout the body, governing more than just sleep and wake cycles — they are crucial to many aspects of […]
January 22, 2021

Beyond changing DNA itself, mutagens also cause errors in gene transcription

Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases. USC Leonard Davis School of Gerontology Assistant Professor Marc Vermulst and colleagues made the discovery by […]
January 22, 2021

Stem cells may correct deformity and restore brain function after childhood disorder

Using stem cells to regenerate parts of the skull, USC scientists partially corrected a skull deformity and reversed learning and memory deficits in young mice with craniosynostosis, a condition estimated to affect 1 in every 2,500 infants born in the United States. The only current therapy is complex surgery within […]
January 22, 2021

Study finds evidence of lasting immunity after mild or asymptomatic Covid-19 infection

The study, published in Science Immunology, analysed antibody and T cell responses in 136 London healthcare workers who had mild or asymptomatic Covid-19 infection dating back to March 2020. The team, including researchers from Queen Mary, Imperial College London and University College London, found that 89 per cent of healthcare workers […]
January 22, 2021

Accurate predictions of ovarian cancer outcome possible with new classification system

Researchers have discovered and identified sub-types of ovarian cancer cells, which can then be used to accurately identify which ovarian cancer subtypes are likely to lead to more severe cancer outcomes – an approach which has been dubbed the ‘Oxford Classification of Carcinoma of the Ovary’ or ‘Oxford Classic’ for […]
January 22, 2021

A healthy heart may help delay or prevent dementia

New study shows targeting arterial stiffening earlier in a person’s lifespan could provide cognitive benefits in older age and may help to delay the onset of dementia. Researchers at the University of Oxford and University College London investigated 542 older adults who received two measurements of aortic stiffness, at 64 […]
January 22, 2021

Motion sensitivity research could benefit people with inner ear condition

Research into motion sensitivity could lead to improved rehabilitation programmes and an improvement in building designs for people with a rare inner ear condition that affects their balance. Dr Jessica Tyrrell at the University of Exeter’s Medical School will use the VSimulators research facility at Exeter Science Park to explore the response […]
January 22, 2021

Gut bacteria help digest dietary fiber, release important antioxidant

Dietary fiber found in grains is a large component of many diets, but little is understood about how we digest the fiber, as humans lack enzymes to break down the complex molecules. Some species of gut bacteria break down the fiber in such a way that it not only becomes […]
January 22, 2021

Stretching more effective than walking to lower high blood pressure

A new University of Saskatchewan (USask) study has found that stretching is superior to brisk walking for reducing blood pressure in people with high blood pressure or who are at risk of developing elevated levels. Walking has long been the prescription of choice for physicians trying to help their patients […]
January 22, 2021

Regulating the ribosomal RNA production line

The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant type of RNA within cells, when resources are scarce and the bacteria Escherichia coli needs to slow its growth. Researchers used cryo-electron microscopy (cryo-EM) to capture the structures […]
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