General

Researchers around the world have been puzzled by the different symptoms and varied disease pathways of Parkinson’s patients. A major study from Aarhus University has now identified that there are actually two types of the disease. Although the name may suggest otherwise, Parkinson's disease is not one but two diseases, […]

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin–Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza. In a study published in Cell Reports Medicine, scientists describe a T-cell-based vaccine strategy that is effective […]

Salk researchers develop transplantable human cells that make insulin, controlling blood sugar without immunosuppressants in mouse models Salk Institute scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost […]

Scientists from the Tokyo Institute of Technology, Tokyo Medical University, and Saitama Medical University have published findings that offer insights into how the drug pomalidomide benefits some patients with a cancer called multiple myeloma. Clinicians use pomalidomide to treat cases of multiple myeloma resistant to the more established drug lenalidomide, […]

Researchers at Kanazawa University report in Nature Communications the discovery that in the developing fly brain, neurons stemming from the same parent cell experience repulsion. This lineage-dependent repulsion is regulated by a protein known as Dscam1. The brain’s structure has columnar features, which are hypothesized to arise from nerve cells […]

Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, have discovered a new way to manufacture human red blood cells (RBCs) that cuts the culture time by half compared to existing methods and uses novel sorting and purification methods that are faster, more precise, and less costly. […]

Doctors like to remind patients not to monkey around with their health, suggesting that a good diet and regular exercise improve longevity. A new study on health in chimpanzees, which are the closest species to humans genetically, showed the benefits in what they eat and how they can travel and […]

Understanding of fibromuscular dysplasia (FMD), a rare blood vessel disease, is making the jump from the laboratory to the clinic with new findings of a genetic variant. Researchers found the mutation in a gene that is associated with classical Ehlers-Danlos Syndrome as well, in multifocal FMD. That means it could […]

Adding an immunotherapy agent to a three-drug chemotherapy regimen can improve the likelihood that early-stage triple-negative breast cancer will recede to undetectable levels, data from a clinical trial led by Dana-Farber/Brigham and Women’s Cancer Center suggests. The results of the trial, dubbed the IMpassion031 study, will be presented at the […]

Hard skulls help protect our brains from physical injuries. In addition to a tough outer shell, brains have internal defences, including a powerful shield called the blood-brain barrier that defends brain cells from substances in the bloodstream that are toxic and dangerous to nerve cells. If the blood-brain barrier is […]

Hypertrophic cardiomyopathy is the most common inherited heart disease, marked by an abnormally thickened heart muscle that can obstruct blood flow and lead to sudden death in young adults. A dizzying array of over 1,400 genetic mutations can lead to the disease, puzzling doctors on how to treat so many […]

Macrophages of the innate immune system, cells derived from monocytes, are involved in many processes in tissue beyond merely hunting down invading pathogens. They are also important to the processes of tissue maintenance regeneration following injury. Like all aspects of the immune system, macrophage behavior becomes dysregulated with age, a […]