General

Researchers at McMaster and Brock universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing. The device works much like the monitors that people with diabetes use to test their blood-sugar […]

New research shows a simple skin test can accurately identify Parkinson’s disease, demonstrating for the first time the feasibility of the method. Currently diagnosed by clinical signs and symptoms but only definitively diagnosed at autopsy, Parkinson’s disease is commonly misdiagnosed early in the disease course, complicating clinical trials of potential […]

Extracellular vesicles (EVs), nanometer-sized messengers that travel between cells to deliver cues and cargo, are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injuries. EVs have already been shown to help heart cells recover after a heart attack, but […]

This phase 2 trial also identified a subset of patients with specific mutations who may see the most benefit from the drug. When first- and second-line treatments have been exhausted, few options remain for patients with advanced head and neck cancer. A new phase 2 clinical trial by researchers at […]

Pharmaceutical maker Eli Lilly and Company have purchased Disarm Therapeutics, a startup biotechnology firm founded by researchers at Washington University School of Medicine in St. Louis. Disarm Therapeutics was co-founded by Jeffrey Milbrandt, MD, PhD, and Aaron DiAntonio, MD, PhD, to speed the development of treatments for multiple neurodegenerative conditions. Based […]

Intranasal administration of an anti-inflammatory drug helped reduce disease progression in a preclinical model of multiple sclerosis, according to recent research out of the University of Alberta. Christopher Power, a professor in the Faculty of Medicine & Dentistry, and Leina Saito, a graduate student on his team, showed that delivering an anti-inflammatory […]

New generation CRISPR technology lays foundation for therapeutics to treat a wide range of inherited ocular diseases. A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease. Published in Nature Biomedical […]

Large repository of blood samples from military personnel provides invaluable resource for PNNL biomedical scientists Routine serial blood draws during military personnel’s service are proving to be an invaluable bank of specimens for health researchers. Using samples collected at enlistment, every two years for HIV testing, and at pre-deployment and post-deployment, […]

Humans aren’t born with mature brain circuitry that attaches emotions to the things they see or hear in their environment, a new study shows. Researchers studying brain scans of newborns found that the part of the brain involved in experiencing emotions isn’t functionally connected in a mature way with the […]

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell’s genome, according to a new study by UC San Francisco […]

Hair loss seems like a minor problem to many. You got bald, so what? Some people prefer this look. However, for many men going bald is a terrible experience and they would pay good money to avoid it. Now scientists at the University of Helsinki have identified a mechanism that […]

Multidrug resistance (MDR) – a process in which tumours become resistant to multiple medicines –– is the main cause of failure of cancer chemotherapy. Tumour cells often acquire MDR by boosting their production of proteins that pump drugs out of the cell, rendering the chemotherapies ineffective. Now, researchers reporting in […]