September 20, 2019

Eisai and Meiji Announce Parkinson's Disease Treatment Equfina Tablets (Safinamide Mesilate) Approved In Japan

Eisai Co., Ltd. and Meiji Seika Pharma Co., Ltd. has announced the manufacturing and marketing approval in Japan for the indication of improvement of wearing-off phenomenon in patients with Parkinson's disease under treatment with a drug containing levodopa for Equfina TABLETS (safinamide mesilate, “safinamide”), which was developed for use in […]
September 20, 2019

Heart Function: Built to Endure

Major physical changes occurred in the human heart as people shifted from hunting and foraging to farming and modern life. As a result, human hearts are now less “apelike” and better suited to endurance types of activity. But that also means those who lead sedentary lives are at greater risk for […]
September 20, 2019

Brain tumors form synapses with healthy neurons, Stanford-led study finds

Scientists at the Stanford University School of Medicine have shown for the first time that severe brain cancers integrate into the brain’s wiring. The tumors, called high-grade gliomas, form synapses that hijack electrical signals from healthy nerve cells to drive their own growth. Experiments demonstrated that interrupting these signals with an existing […]
September 20, 2019

Study gives the green light to the fruit fly’s color preference

For more than a century, the humble and ubiquitous fruit fly has helped scientists shed light on human genetics, disease, and behavior. Now a new study by University of Miami researchers reveals that the tiny, winged insects have an innate time- and color-dependent preference for light, raising the intriguing possibility […]
September 20, 2019

Cancer cells turn to cannibalism to survive chemotherapy

Researchers from Tulane University School of Medicine have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study, which was published in the Journal of Cell Biology, suggests that this act of cannibalism provides these cancer cells with the energy they need to stay alive and initiate tumor […]
September 19, 2019

Early maternal anemia tied to intellectual disability, ADHD and autism

The timing of anemia—a common condition in late pregnancy—can make a big difference for the developing fetus, according to research at Karolinska Institutet published in JAMA Psychiatry. The researchers found a link between early anemia and increased risk of autism, ADHD and intellectual disability in the child. Anemia discovered toward […]
September 19, 2019

Multi-institutional team to study effects of age, gender on brain injury mechanics

Traumatic brain injury and chronic traumatic encephalopathy (CTE) have become common in athletes who suffer repeated blows to the head. Most recently, former New England Patriots tight end Rob Gronkowski revealed that he had sustained about 20 concussions during his nine-year career in the National Football League. Now, a team […]
September 19, 2019

Regulatory heft needed to curb false promises on stem cells, says health law expert

The legal and regulatory tools designed to protect the public from the marketing of unproven stem cell therapies will remain ineffective without bureaucratic will and grassroots efforts, according to a University of Alberta health law expert. “There's this perception that stem cells are revolutionizing science and they have transformed medicine […]
September 19, 2019

Study points to new drug target in fight against cancer

Researchers have identified a potential new drug target in the fight against cancer. In a study in the Proceedings of the National Academy of Sciences, an international team of researchers describe how a cancer-linked version of the protein mitoNEET can close the primary gateways in the outer surface of mitochondria, the “power plants” […]
September 19, 2019

Testing chemicals for birth defects using stem cells, not mice

Researchers at the University of California, Riverside, are part of an ambitious plan at the U.S. Environmental Protection Agency, or EPA, to eliminate animal testing by 2035. Their contribution: developing a way to test whether chemicals cause musculoskeletal birth defects using lab-grown human tissue, not live animals. Nicole zur Nieden, an […]
September 19, 2019

Once-common hysterectomy technique linked to worse uterine cancer outcomes

Every year, nearly 700,000 American women have surgery to remove their uterus (hysterectomy) or uterine fibroids (myomectomy). A laparoscopic surgical technique once commonly used in these procedures could be worsening the outcomes for women who have undiagnosed uterine cancer at the time of the procedure, reports a Yale-led study in the […]
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