General

Our bodies hold roughly 14 trillion cells, each containing a nucleus with DNA measuring two meters long by 20 atoms wide. To fit inside each nucleus, DNA coils around specialized proteins. These spools of wrapped DNA inhibit gene regulatory proteins from binding to protein-coding stretches along the genome, which help […]

Pairing a novel personalized cancer vaccine with an established immunotherapy drug administered to patients in a new way, Harvard Medical School scientists at Dana-Farber Cancer Institute are testing a first-of-its-kind strategy aimed at improving outcomes for kidney cancer patients who are at high risk of recurrence following surgery. This two-pronged approach to […]

Lifestyle changes often follow a cancer diagnosis, both during treatment and after. Eating well is often the first step. And there is good reason for it. A healthy diet can help prolong life for cancer patients and cancer survivors, says University of Michigan Rogel Cancer Center member Suzanna Zick, N.D., MPH. Surveys show […]

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for alternatives. Researchers from Case Western Reserve University School of Medicine, Argonne National Laboratory and the Lawrence […]

Cancer is a complex set of diseases that researchers are studying to improve therapy and develop prevention strategies. Although there is no single way to prevent cancer, oncologists agree that taking steps to mitigate risk is key. Experts at The Ohio State University Comprehensive Cancer Center – Arthur G. James […]

New research from The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) underscores the importance of genomic analysis of rare malignant tumors that are genetically unstable and have high numbers of gene mutations. OSUCCC – James investigators […]

A study published today in eLife, led by University of Wisconsin–Madison Professor of Biochemistry and Bacteriology Robert Landick and his research team, reveals for the first time the elemental mechanism behind transcriptional pausing, which underlies the control of gene expression in all living organisms. It also provides new understanding of the enzyme RNA polymerase, an […]

Bone marrow transplants, which involve transplanting healthy blood stem cells, offer the best treatment for many types of cancers, blood disorders and immune diseases. Even though 22,000 of these procedures are performed each year in the US, much remains to be understood about how they work. A new USC and […]

About 31 million U.S. adults have food allergies, nearly half of which develop after age 18, according to a study published in JAMA Network Open. The research, a collaboration between Stanford food allergy expert Kari Nadeau, MD, PhD, and scientists at Northwestern University, is the first comprehensive examination of the prevalence of food allergies […]

A new study by Keck School of Medicine of USC researchers shows there's yet another reason to avoid high fat, high cholesterol diet: It can trigger changes in the immune system that lead to a serious form of non-alcoholic fatty liver diseases (NAFLD) known as non-alcoholic steatohepatitis (NASH). NAFLD is […]

Researchers from The University of Western Australia have conducted a study that has found young women who start having periods early and often have a high body mass index are more prone to cardiovascular problems later in life such as heart disease, stroke and diabetes. More than 800 young women […]

Undifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteristics of clinical importance – a new study at Karolinska Institutet reveals. The results, published in the journal Clinical Cancer Research, also show that the survival rate of patients with […]