March 17, 2021

Supercomputing the secrets of the inner ear

The ears don't just help you hear. They also help a person walk, stand, and stay balanced. In fact, they work together with other systems in the body to help one understand our place in space. Many people who have sensations of vertigo find that the problem lies in their […]
March 17, 2021

Stem cell scientists start a buzz around fruit flies in hearing research

Even though a fruit fly doesn’t have ears, it can hear with its antennae. In a study published in the journal Development, USC Stem Cell scientists describe how adult flies can regenerate sensory hearing cells in their antennae, and how studying flies can provide a new way to understand and […]
March 17, 2021

Supercomputers Help Accelerate Alzheimer’s Research

Since 2009, Daniel Tward and his collaborators have analyzed more than 47,000 images of human brains via MRI Cloud—a gateway created to collect and share quantitative information from human brain images, including subtle changes in shape and cortical thickness. The latter was the topic of a recently published study in the […]
March 17, 2021

How to Speed Up Muscle Repair

A study led by researchers at the University of California San Diego Jacobs School of Engineering provides new insights for developing therapies for muscle disease, injury and atrophy. By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be […]
March 17, 2021

Researchers link breast cancer and bone growth

Breast cancer poses a substantial threat as it spreads to other organs, often lying in wait for years in these tissues and recurring without warning. Bones are a prime target, but the mechanisms that influence whether skeletal metastasis will develop or not remain poorly understood. A collaboration between researchers at […]
March 17, 2021

Stimulating the Immune System to Fight Cancer

Cancer cells have evolved mechanisms to escape the body's immune defense. Agents that prevent immune escape are attractive targets for the development of new cancer therapies. A group of scientists led by Herbert Waldmann and Slava Ziegler at the Max Planck Institute of Molecular Physiology in Dortmund has now developed […]
March 17, 2021

Piperlongumine Reduces Aortic Calcification in Mice

Piperlongumine, an extract of long peppers, was shown to be senolytic a few years ago. The compound is capable of selectively destroying senescent cells by sensitizing them to oxidative damage, provoking apoptosis. The accumulation of senescent cells is one of the causes of aging, and means of clearance are thus […]
March 17, 2021

Inclusive Autism Screening

Screening tools for autism spectrum disorder (ASD) often fail to identify ASD among children from low-income families and racial/ethnic minority groups, particularly when English is not the family’s primary language. A new visually-based tool may reduce these disparities at a pivotal point in children’s development. In Pediatrics, Zuleyha Cidav, David Mandell, and colleagues found […]
March 17, 2021

Head Injury 25 Years Later – Study Finds Increased Risk of Dementia

Head injury in the United States is common, with over 23 million adults age 40 or older reporting a history of head injury with loss of consciousness. Many head injuries can be caused by a host of different situations – from car and motorcycle accidents to sports injuries. What’s more, it […]
March 17, 2021

Babies pay attention with down payment from immature brain region

Anyone who has watched an infant’s eyes follow a dangling trinket dancing in front of them knows that babies are capable of paying attention with laser focus. But with large areas of their young brains still underdeveloped, how do they manage to do so? Using an approach pioneered at Yale […]
March 17, 2021

94% of older adults prescribed drugs that raise risk of falling

Nearly every older adult has prescribed a prescription drug that increased their risk of falling in 2017, according to new University at Buffalo research. The study found that the percentage of adults 65 and older who were prescribed a fall- risk-increasing drug climbed to 94% in 2017, a significant leap […]
March 16, 2021

International Alzheimer’s clinical trial to test tau drugs

A worldwide clinical trial aimed at finding treatments for Alzheimer’s disease has expanded to include investigational drugs targeting a harmful form of the brain protein tau. The trial, known as the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) and led by Washington University School of Medicine in St. Louis, launched […]
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