General

Researchers at University of California San Diego School of Medicine say the loss of a single gene two to three million years ago in our ancestors may have resulted in a heightened risk of cardiovascular disease in all humans as a species, while also setting up a further risk for […]

Studies: widespread aspirin use has few benefits, high risk. Medical consensus once supported daily use of low-dose aspirin to prevent heart attack and stroke in people at increased risk for cardiovascular disease. But in 2018, three major clinical trials cast doubt on that conventional wisdom, finding few benefits and consistent […]

Families living with extremely rare neurodegenerative diseases finally received an answer to the cause of their illnesses, thanks to a researcher’s hunch and decades of improvements in DNA sequencing technology. Four different rare diseases are all caused by the same short segment of DNA repeated too many times, a mutation […]

A study of newborn infants has identified a compound produced by gut bacteria that appears to predispose certain infants to allergies and asthma later in life. “We have discovered a specific bacterial lipid in the neonatal gut that promotes immune dysfunction associated with allergic asthma and can be used to […]

Fifty years ago this month, the Apollo 11 mission landed on the moon, and the first human being took “one small step” onto its surface. Now, the buzz is around getting humans to Mars, and, according to a new report on research in rats published in Frontiers in Physiology, the first […]

A new University at Buffalo-led study supported by NSF describes how researchers wirelessly controlled FGFR1 — a gene that plays a key role in how animals grow from embryos to adults — in lab-grown brain tissue. The ability to manipulate the gene, the study's authors say, could one day lead to […]

The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide reductase that may avoid the toxicity of previous approaches, informing focused drug discovery efforts. The results were published in Nature Communications. Ribonucleotide reductase controls […]

A gene linked to Alzheimer’s disease may impact cognitive health much sooner than previously realized. The APOE gene creates a protein, apolipoprotein E, which packages cholesterol and other fats to transport them through the bloodstream. There are three versions, or alleles, of APOE. One of those is the APOE4 allele, […]

Every cell in your body has a copy of your genome, tightly coiled and packed into its nucleus. Since every copy is effectively identical, the difference between cell types and their biological functions comes down to which, how and when the individual genes in the genome are expressed, or translated […]

Frustrated that her sweater got lost in the community laundry, 92-year-old Gigi took advantage of an embroidery machine to label two others. Jewelry lover Betty had been reluctant to wear her fine necklaces, fearful they would get tangled in the tubes of her oxygen mask, so the 96-year-old found a […]

Researchers from The George Institute for Global Health determined that this differential was greater in type 1 than type 2 diabetes. Type 1 diabetes is associated with a 47% excess risk of heart failure in women compared to men, whilst type 2 diabetes has a 9% higher excess risk of […]

When patients who smoke begin cancer treatment at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis — or at any of Siteman’s satellite locations — they also now receive advice about quitting smoking, referrals to easy-access smoking-cessation services and, if suitable, prescriptions for medications that […]