General

Mitochondria are the power plants of our cells and play an important role in providing energy for normal function of the tissues in our body. Nerve cells are particularly dependent on mitochondria for their activity and decreased mitochondrial function is seen in both inherited and more common age-associated forms of […]

Research published in Nature Medicine examines the clinical characteristics of paediatric inflammatory multisystem syndrome (PIMS-TS). PIMS-TS is a rare syndrome which has emerged in a small number of children during the COVID-19 pandemic. The condition causes severe inflammation in blood vessels and can lead to heart damage. A team from […]

A recent study in Science Advances by researchers at Karolinska Institutet and Max Planck Institute shows that neurons can counteract degeneration and promote survival by adapting their metabolism. It challenges the long-standing view that neurons cannot adjust their metabolism and therefore irreversibly degenerate. These findings may contribute to developing therapeutic […]

Researchers at Vanderbilt University have, for the first time, being able to trigger the specific immune system response required to reverse the course of small intestinal inflammation by inducing the production of tuft cells, very rare epithelial cells that sense and respond to parasites. The breakthrough has the potential to […]

New research could improve the odds that people with the obsessive-compulsive disorder will receive a therapy that really works for them – something that eludes more than a third of those who currently get OCD treatment. The study, performed at the University of Michigan, suggests the possibility of predicting which […]

Pancreatic islet transplants, which revive insulin production to treat type 1 diabetes, only last an average of three years. By learning from a groundbreaking cancer treatment strategy based on a recent Nobel Prize-winning discovery, researchers at the Georgia Institute of Technology and the University of Missouri developed a new microgel […]

Small particles released by cancer cells contain specific proteins that may be used in a blood test to detect cancer at an early stage, according to a study published in the scientific journal Cell by a group of investigators from US institutions, and including a principal author from LiU. Early […]

A new diagnostic tool that can predict whether a cancer patient would respond to immunotherapy treatment has been developed by scientists at the University of Bath. This advance in precision medicine will allow clinicians to tailor treatments specifically to patients and avoid treatment paths that are unlikely to be successful. […]

Childhood and adolescent obesity is projected to contribute up to 14 per cent of overall risk of Multiple Sclerosis (MS) in 2035, according to research led by Queen Mary University of London. Previous studies have estimated that 53 per cent of MS risk is directly attributable to environmental factors, and […]

When autumn comes we wrap ourselves in scarfs and overcoats and enjoy the changing seasons. Meanwhile animals start thinking about the issues of survival, because the beginning of the cold part of the year means that available resources will be scarce again. But how do animals actually adapt to seasons? […]

Scientists from Trinity have discovered a new link between impaired brain energy metabolism and delirium – a disorienting and distressing disorder particularly common in the elderly and one that is currently occurring in a large proportion of patients hospitalised with COVID-19. While much of the research was conducted in mice, […]

Every time you flex your bicep or stretch your calf muscle, you put your cells under stress. Every move we make throughout the day causes our cells to stretch and deform. But this cellular deformation can be dangerous, and could potentially lead to permanent damage to the DNA in our […]