December 20, 2019

Breakthrough research offers new hope to lupus patients

A ‘life-changing’ potential new drug could be available to lupus patients in the future thanks to ‘breakthrough’ research. The results of the TULIP II study have been published in the New England Journal of Medicine (NEJM), one of the most prestigious, peer-reviewed medical journals in the world. TULIP stands for ‘Treatment […]
December 20, 2019

New study on liver humanized mice as a new model system for cholesterol lipoprotein metabolism and pharmacodynamics in humans

Researchers at Karolinska Institutet, together with colleagues from the EU-funded project HUMAN, recently published a study on a new animal model for studies of human lipoprotein metabolism and pharmacodynamics. The study is a result of the EU project HUMAN using a new animal model and new technologies to study aging […]
December 20, 2019

Glutamine may decrease obesity-linked inflammation

Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types. However, […]
December 20, 2019

Fibroblasts Involved in Healing Spur Tumor Growth in Cancer

The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the site of a wound, instigating an inflammatory response that mends damaged tissue. A new Tel Aviv University study published in Nature Communications finds that fibroblasts also play a devastating role in the […]
December 20, 2019

A new role for a triple-negative breast cancer target

Unlike almost every other organ, the mammary gland does not develop until after birth. And it’s unusually dynamic, shape-shifting during menstrual cycles, puberty, pregnancy, and lactation. These changes require energy. In a study using a new, genetically altered mouse model, researchers led by Rumela Chakrabarti of Penn’s School of Veterinary Medicine have uncovered a key protein […]
December 20, 2019

Tackling Glioblastomas: Defeating a Deadly Foe

Each year, roughly 15,000 Americans are diagnosed with Glioblastoma Multiforme (GBM), the most common malignant primary brain tumor in adults… and also the most lethal. Surgery, radiation, and chemotherapy can help slow the tumor’s growth, but the disease remains incurable. Recurrence occurs in almost every case. But the tide to […]
December 20, 2019

Comparing heirloom and modern wheat effects on gut health

Amid concerns about gluten sensitivity, increasing numbers of people are avoiding wheat. Most have not been diagnosed with a wheat-related medical condition, yet they seem to feel better when they don’t eat gluten-containing foods. A possible explanation is that modern varieties of wheat are responsible. But now, researchers reporting in […]
December 20, 2019

Saccharin derivatives give cancer cells a not-so-sweet surprise

Saccharin received a bad rap after studies in the 1970s linked consumption of large amounts of the artificial sweetener to bladder cancer in laboratory rats. Later, research revealed that these findings were not relevant to people. And in a complete turnabout, recent studies indicate that saccharin can actually kill human […]
December 20, 2019

Study may explain how infections reduce autism symptoms

For many years, some parents have noticed that their autistic children’s behavioral symptoms diminished when they had a fever. This phenomenon has been documented in at least two large-scale studies over the past 15 years, but it was unclear why fever would have such an effect. A new study from […]
December 20, 2019

Why Your First Battle With Flu Matters Most?

The first strain of influenza virus we encounter during childhood sets the course of how our immune system responds to exposures later in life. How successfully a person can fend off the flu depends not only on the virus' notorious ability to change with the season, but also on the […]
December 19, 2019

A way to ‘fingerprint’ human cells

Researchers say a new method to analyse data from individual human cells could be a step-change for diagnosing some of the most devastating diseases, including cancer and autoimmune disease. By combining single cell analysis techniques with machine learning algorithms, a team led by researchers at the Garvan Institute of Medical […]
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