March 29, 2019

Testosterone discovery may explain low levels in men with diabetes

Scientists at the University of Virginia and elsewhere have mapped out how the body transports testosterone, and their surprising findings may explain low testosterone levels seen in men with diabetes or patients on certain medications. The discovery allows scientists to understand exactly how testosterone, the male sex hormone, binds to a […]
March 29, 2019

Clear Advance for Corneal Regeneration

An adhesive gel packed with light-activated chemicals can seal cuts or ulcers on the cornea, the clear surface of the eye, and then encourage the regeneration of corneal tissue, according to a preclinical study by Harvard Medical School researchers at Massachusetts Eye and Ear published online in Science Advances. The new […]
March 29, 2019

Personalized in vitro model enables drug screening for kidney cancer

A new UW Carbone Cancer Center study, published online in EBioMedicine, has developed a model that mimics the tumor’s blood supply on a three-dimensional  platform designed in the laboratory of Dr. David Beebe, professor of biomedical engineering and pathology. The authors of the study, led by Drs. Jose “Tony” Jimenez-Torres and Maria […]
March 29, 2019

Engineered Vessels Evolve into Living Tissue

In one of the longest follow-up studies of its kind, researchers found that their specially bioengineered blood vessels evolved into living tissue after human implantation. Researchers from Yale and the North Carolina-based company Humacyte published results in Science Translational Medicine on the progress of their bioengineered human vessels (HAVs). The results show […]
March 28, 2019

Study: Brain Stem Cells Age Faster in MS Patients

Brain stem cells in people with the most severe form of multiple sclerosis look much older than they really are, according to a study led by UConn Health and published in the Proceedings of the National Academy of Sciences (PNAS). The prematurely old cells act differently in the brain than normal ones, […]
March 28, 2019

Study gives new perspective on production of blood cells and immune cells

A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system. How all the different kinds of mature blood cells are derived from the […]
March 28, 2019

Study in mice examines impact of reused cooking oil on breast cancer progression

A new study in mice suggests that consuming the chemical compounds found in thermally abused cooking oil may trigger genetic changes that promote the progression of late-stage breast cancer. Thermally abused frying oil – cooking oil that has been repeatedly reheated to high temperatures – may act as a toxicological […]
March 28, 2019

Lab grown "brains" successfully model disease

The human brain is one of the most complex organs. Its complexity challenges our ability to study its structure and function. As a result, many brain-related diseases are not fully understood and adequate treatments are often lacking. Scientists from Max Planck Institute of Psychiatry were able to model a developmental […]
March 28, 2019

Obesity and emotional problems develop together as children age, study shows

High BMI and mental ill-health go increasingly hand-in-hand to present a combined health risk for children from mid-childhood, according to a new study. Researchers from the University of Liverpool and University College London analysed data on more than 17,000 children born across the UK in 2000-01, who are taking part […]
March 28, 2019

Tumor-Associated Immune Cells Hinder Frontline Chemotherapy Drug in Pancreatic Cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug’s action, research led by the University of Michigan Rogel Cancer Center found.The chemotherapy drug gemcitabine is an anti-metabolite. It’s similar to normal metabolites taken up by the […]
March 28, 2019

New Study Identifies Causative Genes in Osteoporosis

Researchers identified two novel genes that affect bone-formation cells relevant to fractures and osteoporosis; understanding these genes could lead to more effective treatments. Examining a person’s DNA can help scientists understand if the individual is at risk for osteoporosis, the chronic bone-weakening condition that affects millions of Americans. In a […]
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