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Scientists in the Perelman School of Medicine at the University of Pennsylvania have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM), an often-fatal heart disorder. This inherited form of DCM — which affects at least several thousand people in the United States at any one time […]

A simple non-invasive test can accurately detect womb cancer according to a proof of concept study by University of Manchester and Manchester University NHS Foundation Trust (MFT) scientists. The non-invasive test, which detects cancer by looking at urine or vaginal sample with a microscope, could have a major benefit for patients if […]

Variants of nine genes increase the risk of developing Addison’s disease, a rare disease in which the immune system attacks the adrenal glands. That is according to the largest genetic study to date on patients with Addison’s disease. The findings help increase knowledge about what causes the disease. The study […]

Neuroblastoma arises within the sympathetic nervous system and is the most frequent extracranial solid childhood cancer, exhibiting a high degree of clinical heterogeneity ranging from spontaneous regression to fatal progression despite intense clinical intervention. Despite extensive sequencing efforts, the number of identified recurrent mutations remain low in pediatric neuroblastoma. Researchers […]

In people with Crohn’s disease, a chronic inflammatory bowel condition, symptoms or how they feel may not line up with actual inflammation in their gut. This mismatch creates challenges for accurately measuring how well a treatment is truly working, especially for children. Currently, many gastroenterologists use symptoms and blood tests […]

A research paper published in the New England Journal of Medicine has revealed that a new anti-obesity medication is almost twice as effective in helping people lose weight than other current weight loss drugs. Professor John Wilding, who leads clinical research into obesity, diabetes and endocrinology at the University of […]

Glycomics researchers at the University of Alberta and CHU Sainte-Justine have reported a discovery that could lead to new treatments for cardiovascular disease. The researchers identified a new mechanism responsible for the buildup of plaque on artery walls, a process known as atherosclerosis. This plaque, made up of fats, cholesterol […]

Genetics and multi-omic information could one day inform treatments for glioblastoma. The largest and most detailed molecular analysis yet of an aggressive brain cancer, called glioblastoma, reveals fundamental details that drive its growth. The work, led by a team of scientists from the U.S. Department of Energy’s (DOE) Pacific Northwest […]

Dance is considered as one of the art forms. Regardless of whether we do it professionally or as a hobby, it gives us great pleasure, relaxes, and allows us to break away from the prose of life. Thus, dance can be beneficial for our mind, memory, stimulation of the nerve […]

IMDEA Nanociencia researchers measure the nanoscale heating of gold-based nanoparticles and find high temperature variations within a nanoscopic volume. In hyperthermia treatments, the temperature is raised above physiological levels to induce the death of cancerous cells. The local application of hyperthermia is key for a successful treatment and to reduce […]

Researchers at the Garvan Institute of Medical Research have developed a computational model to calculate ‘skeletal age’, a personalised estimate of an individual’s risk of bone fracture and premature death. The skeletal age calculator, which will be accessible to doctors and health professionals, aims to better identify those at risk […]

Exposure to radiation can wreak indiscriminate havoc on cells, tissues, and organs. Curiously, however, some tissues are more vulnerable to radiation damage than others. Scientists have known these differences involve the protein p53, a well-studied tumour-suppressor protein that initiates a cell’s auto-destruct programs. Yet, levels of this sentinel protein are […]