July 2, 2019

Researchers unlock mysteries of complex microRNA oncogenes

MicroRNAs are tiny molecules of nucleic acid that control gene expression, acting like a dimmer switch to tone down gene output at key positions in the network of information that governs a cell’s function. MicroRNAs are important for the day-to-day inner working of cells and especially important during development. They […]
July 2, 2019

Boosting the cancer-destroying ability of killer T-cells

The team of researchers discovered that increasing the amount of the molecule L-selectin on T-cells can vastly improve their ability to fight solid tumours. Professor Ann Ager, from Cardiff University’s Systems Immunity Research Institute, said: “These results mean that immunotherapy could be used to fight most cancers. This is great […]
July 2, 2019

Moments of Clarity, Glimmers of Hope

It happens unexpectedly: a person long thought lost to the ravages of dementia, unable to recall the events of their lives or even recognize those closest to them, will suddenly wake up and exhibit surprisingly normal behavior, only to pass away shortly thereafter. This phenomenon, which experts refer to as […]
July 2, 2019

Does Anesthesia, Invasive Surgery Increase Multiple Sclerosis Relapse Risk?

A recent Multiple Sclerosis Journal study that included data from 281 patients and 609 surgeries suggests post-operative MS relapse risk does not significantly differ from pre-operative relapse risk. No prior studies have systematically investigated the influence of surgery or anesthesia administration on relapse risk, but it’s a large concern in clinical practice. This […]
July 1, 2019

Protein-linked sugars are crucial for the uptake of proteins linked to Parkinson’s disease

Parkinson’s disease, a neurodegenerative disorder that affects more than 6 million people worldwide, is caused by the buildup of alpha-synuclein proteins in the brain. The biological function of alpha-synuclein is still not well understood, but because of its role in neurodegenerative diseases, researchers are actively studying this protein to understand […]
July 1, 2019

New research raises possibility of better anti-obesity drugs

Effective weight-loss strategies call for eating less food, burning more calories — or ideally, both. But for the more than 90 million Americans who suffer from obesity, a disease that contributes to conditions ranging from heart disease to cancer, behavioral change is hard to accomplish or not effective enough, which […]
July 1, 2019

Pigs help scientists understand human brain

For the first time, researchers in the University of Georgia’s Regenerative Bioscience Center have used an imaging method normally reserved for humans to analyze brain activity in live agricultural swine models, and they have discovered that pig brains are even better platforms than previously thought for the study of human neurological […]
June 30, 2019

Confining cell-killing treatments to tumors

Cytokines, small proteins released by immune cells to communicate with each other, have for some time been investigated as a potential cancer treatment. However, despite their known potency and potential for use alongside other immunotherapies, cytokines have yet to be successfully developed into an effective cancer therapy. That is because […]
June 28, 2019

When a Rare Mutation Causes a Rare Disease: Jacob’s Story

For some parents, a physician’s advice to “just take him home and love him,” presumably letting nature take it’s most likely course, is just not acceptable. This blog has championed many such parents, who serve as catalysts for others. New to rare disease territory is Orah Lasko, whose toddler Jacob not […]
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