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Biologists have known for some time that RNA interference can silence genes in far-​off cells. They suspected that a messenger substance “transmits” RNA interference. Now, ETH researchers have definitively shown that these messengers in plants are short double-stranded RNA fragments. In most organisms, small bits of RNA play a key […]

Cancer researchers Alex Huang, Reshmi Parameswaran, and Yamilet Huerta have been awarded $315,000 in grants from the St. Baldrick’s Foundation to conduct research of new immunotherapy treatments for pediatric cancers. Huang, professor of pediatrics at Case Western Reserve University School of Medicine and co-leader of the Hematopoietic and Immune Cancer […]

New technologies accelerate high-resolution imaging of human chromosomes in single cells. The intricate, tightly wound structures of chromosomes condense about two meters of DNA so the complete instruction manual for growing a human can be tucked inside a cell nucleus just 10 microns wide. “This is like fitting something the […]

A new study, which analyzed 40 years of Framingham Heart Study data, found an association between lowered rates of hip fractures and decreases in smoking and heavy drinking. The rates of hip fractures in the United States have been declining over the past few decades. Although some experts attribute this […]

The self-eating process in embryonic stem cells known as chaperone-mediated autophagy (CMA) and a related metabolite may serve as promising new therapeutic targets to repair or regenerate damaged cells and organs, Penn Medicine researchers show in a new study published online in Science. Human bodies contain over 200 different types of specialized cells. […]

Yale School of Medicine and the biopharmaceutical firm AI Therapeutics have launched a multi-institutional clinical trial of a drug for treating COVID-19. Known as LAM-002A (apilimod), the drug has a proven safety record. Preliminary research has shown it can block cellular entry and trafficking of the SARS-CoV-2 virus, the cause […]

Human pregnancy can easily be taken for granted as a natural and regularly occurring event, but it is the product of the complex, coordinated function of two bodies, mother and baby, that has evolved side by side with other important human adaptations. For the first time, researchers have established how […]

The number of people in the U.S. living with Alzheimer’s or dementia is expected to triple by 2050, and the latest research from the Alzheimer’s Association shows that half of the medical providers are not prepared to care for them. Now, new recommendations from a National Institutes of Health working group on […]

When our neurons — the principal cells of the brain — die, so do we. Most neurons are created during embryonic development and have no “backup” after birth. Researchers have generally believed that their survival is determined nearly extrinsically, or by outside forces, such as the tissues and cells that neurons supply with […]

New method to improve the diagnosis of genetic diseases. Breaks and rearrangements in the genome can lead to severe diseases, even if all genes remain intact. Hi-C, a method to map the three-dimensional structure of chromosomes, promises more reliable and accurate diagnoses of such defects, but is not used in […]

Research from The University of Western Australia has found a diet rich in nutrients and antioxidants may prevent or even reverse the effects of Alzheimer’s disease. The study, published in Open Biology, found taking a combination of antioxidants at increasing doses was more beneficial at preventing the debilitating disease than any other […]

Early menstruation increases the likelihood of hot flushes and nights sweats decades later at menopause, according to a University of Queensland study. School of Public Health researchers analysed data from more than 18,000 middle aged women across the UK, USA and Australia, as part of the Life course Approach to reproductive health and Chronic […]