November 30, 2020

A Look at the Damage Done by Senescent T Cells in the Aged Immune System

Cells become senescent and cease replication in response to damage, a toxic environment, or reaching the Hayflick limit. Such cells near all self-destruct or are destroyed by the immune system. In later life, however, they begin to linger and accumulate. This is an issue, as the secretions of senescent cells […]
November 30, 2020

Gilberto Fisone receives grant for international collaboration within personalised medicine for neurodegenerative diseases (JPND)

Gilberto Fisone has been awarded a three-year research grant from the Swedish Research Council within the program Novel Imaging and Brain Stimulation Methods and Technologies (JPND) for a project entitled “Phage-based targeted neural stimulation in neurodegenerative diseases”. ”Parkinson’s Disease is one of the most common neurodegenerative diseases with major social […]
November 30, 2020

How we learn words and sentences at the same time

How people work out the meanings of new words has been revealed by Lancaster University researchers, who say this is similar to the way in which young children learn the language. The research published in Cognition is by Professor Patrick Rebuschat and Professor Padraic Monaghan, who said: “Have you ever caught yourself […]
November 28, 2020

Study revealing the secret behind a key cellular process refutes biology textbooks

New research has identified and described a cellular process that, despite what textbooks say, has remained elusive to scientists until now – precisely how the copying of genetic material that, once started, is properly turned off. The finding concerns a key process essential to life: the transcription phase of gene […]
November 27, 2020

Gene analysis may increase the effect of antidepressant and antipsychotic drugs

In a new study published in the journal JAMA Psychiatry, researchers at Karolinska Institutet have studied CYP2C19 and CYP2D6 genes impact on treatment with antidepressants and antipsychotic drugs. The study shows that control of the patient’s genotype can be used to individualize the drug treatment and lead to a more […]
November 27, 2020

Hot spots identified for colorectal cancer mortality rates among young women

Women diagnosed with early-onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology. The study is the first to define specific geographic areas in the United States where women diagnosed with colorectal cancer […]
November 27, 2020

Big Data Powers Design of ‘Smart’ Cell Therapies for Cancer

Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research. In two new papers, scientists at UC San Francisco and Princeton University present complementary strategies to crack this problem with “smart” cell therapies – living medicines that remain inert unless triggered […]
November 26, 2020

Did early life need long, complex molecules to make cell-like compartments?

Protocell compartments used as models for an important step in the early evolution of life on Earth can be made from short polymers. The short polymers, which better approximate the likely size of molecules available on the early Earth, form the compartments through liquid-liquid phase separation in the same manner […]
November 26, 2020

For Teens with Migraines, Sleeping In (a Bit) May Help

Research indicates that starting school later in the morning yields health and academic benefits for high schoolers, whose natural body clock tends toward late-to-bed, late-to-rise habits. While parents raise concerns about drowsy driving, irritation and impaired school performance, a new study led by researchers at UC San Francisco suggests another […]
November 26, 2020

A gel for dosage compensation

Male fruit flies have only one X chromosome instead of two like their female counterparts. Therefore, their X chromosome must be twice as active to achieve the same “gene dosage”. If this does not succeed, the animals die. Researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg […]
November 26, 2020

‘Monster Tumors’ Could Offer New Glimpse at Human Development

Finding just the right model to study human development—from the early embryonic stage onward—has been a challenge for scientists over the last decade. Now, bioengineers at the University of California San Diego have homed in on an unusual candidate: teratomas. Teratomas—which mean “monstrous tumors” in Greek—are tumors made up of […]
November 26, 2020

Sestrin makes fruit flies live longer

Reduced food intake, known as dietary restriction, leads to a longer lifespan in many animals and can improve health in humans. However, the molecular mechanisms underlying the positive effects of dietary restriction are still unclear. Researchers from the Max Planck Institute for Biology of Ageing have now found one possible […]
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