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Women have an increased risk of high-grade cervical lesions returning after surgery if there have been lesions in the resection margin, especially if high-risk HPV (human papillomavirus) is found in the follow-up test, reports a new longitudinal study from Karolinska Institutet published in The American Journal of Obstetrics and Gynecology. […]

A new method, developed by Banushree Kumar and Simon Elsässer at Karolinska Institutet, produces quantitative maps for modifications of so-called histone proteins that package the DNA molecules in every eukaryotic cell. The study, published in the journal Cell Reports, describes new properties of naïve pluripotent stem cells. Embryonic stem cells […]

Can a computer be used to explain why an environmental toxin might lead to neurodegenerative disease? According to Penn State College of Medicine researchers, a computer generated-simulation allowed them to see how a toxin produced by algal blooms in saltwater might cause Amyotrophic Lateral Sclerosis (ALS). The researchers investigated an […]

Ventrix, a University of California San Diego spin-off company, has successfully conducted a first-in-human, FDA-approved Phase 1 clinical trial of an injectable hydrogel that aims to repair damage and restore cardiac function in heart failure patients who previously suffered a heart attack. The trial is the first to test a […]

Eating your tomato sauce with meatballs piled on top could have a surprising downside, new research suggests. Some of the anti-cancer benefits of tomatoes, specifically those from a compound called lycopene, could disappear when they’re eaten with iron-rich foods, according to a new study from The Ohio State University. Researchers analyzed […]

Case Western Reserve University and Boston-based Akouos have entered into an exclusive licensing agreement to develop a patented gene therapy with the potential to treat hearing loss associated with a type of Usher syndrome,  the most common deaf-blind disorder. Usher syndrome is characterized by partial or total hearing loss and vision loss that worsens […]

A new study led by Harvard Medical School researchers at the MassGeneral Hospital for Children has found that adolescent sleep timing preferences and patterns should be considered risk factors for obesity and cardiometabolic health, and that the effects are greater in girls than in boys. Poor quality and short duration […]

A single high dose of radiation aimed at the heart significantly reduces episodes of a potentially deadly rapid heart rhythm, according to results of a phase one/two study at Washington University School of Medicine in St. Louis. Patients in the study were severely ill and had exhausted other standard treatment […]

Scientists at Washington University School of Medicine in St. Louis appear to have solved a decades-long mystery regarding the precise biochemical pathway leading to a fatal genetic disorder in children that results in seizures, developmental regression and death, usually around age 3. Studying a mouse model with the same human […]

If your child has celiac disease, you will need two of everything in your kitchen—just one source of extra expense faced by families dealing with Canada’s most common autoimmune disorder. A new guide for parents, Growing Up Celiac, recommends that food for celiac children be prepared using a separate toaster, butter […]

Human life expectancy has more than doubled over the last century, and this sudden leap in longevity is triggering major shifts in our politics, economy and society — not to mention our personal health. Next week, UC Berkeley will host the second annual Aging, Research, and Technology Innovation Summit, a daylong […]

People living with inflammatory autoimmune disease could benefit from an ‘immune system reboot’, and researchers have isolated specific cells to target. The University of Queensland’s Professor Ranjeny Thomas said the research findings give hope for similar new immunotherapies for people with diseases like rheumatoid arthritis and vasculitis. “People with these diseases currently […]