January 13, 2021

Neuroscientists identify brain circuit that encodes timing of events

When we experience a new event, our brain records a memory of not only what happened, but also the context, including the time and location of the event. A new study from MIT neuroscientists sheds light on how the timing of memory is encoded in the hippocampus and suggests that […]
January 12, 2021

New insights on the role of the MLL4 gene in Kabuki syndrome

Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder. But a study published in Nature Communications illuminates new details regarding how this occurs. The research suggests that MLL4 controls the production of neurons that secrete growth hormone-releasing hormone (GHRH) in a part […]
January 12, 2021

Brain Cells Most Vulnerable to Alzheimer’s Disease Identified by Scientists

A major mystery in Alzheimer’s disease research is why some brain cells succumb to the creeping pathology of the disease years before symptoms first appear, while others seem impervious to the degeneration surrounding them until the disease’s final stages. Now, in a study published in Nature Neuroscience, a team of […]
January 12, 2021

Nanomaterials for the Clearance of Senescent Cells

Senescent cell accumulation is a contributing cause of aging, and targeted destruction of senescent cells with senolytic therapies produces meaningful rejuvenation and reversal of age-related disease in animal models. First generation senolytics are largely repurposed small molecules. Second generation senolytics will include a range of more carefully designed strategies, including […]
January 11, 2021

Alpha-ray missile therapy: tumor cells attacked from intracellular region

Researchers at Osaka University have developed a technique of attacking cancer cells with lethal alpha rays from within by using a nutrient transporter to deliver radionuclides into malignant tumors A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues. Inhibiting the function of LAT1 has been […]
January 11, 2021

‘Virtual biopsies’ could replace tissue biopsies in future thanks to technique developed by Cambridge scientists

A new advanced computing technique using routine medical scans to enable doctors to take fewer, more accurate tumour biopsies, has been developed by cancer researchers at the University of Cambridge. This is an important step towards precision tissue sampling for cancer patients to help select the best treatment. In future […]
January 11, 2021

Magnets dim natural glow of human cells, may shed light on how animals migrate

Researchers in Japan have made the first observations of biological magnetoreception –  live, unaltered cells responding to a magnetic field in real-time. This discovery is a crucial step in understanding how animals from birds to butterflies navigate using Earth’s magnetic field and addressing the question of whether weak electromagnetic fields […]
January 11, 2021

U of M begins Phase I of first-in-human clinical trial for glioblastoma

Physicians and scientists at the University of Minnesota have opened a new brain cancer clinical trial and have treated their first patient. This Phase I, the first-in-human trial is enrolling patients with a specific type of brain cancer, glioblastoma. The development for this innovative treatment is based on years of […]
January 10, 2021

‘Invisible’ Stem Cells Evade Natural Killer Cells Using Immune ‘Off-Switch’

UC San Francisco scientists have discovered a new way to control the immune system’s “natural killer” (NK) cells, a finding with implications for novel cell therapies and tissue implants that can evade immune rejection. The findings could also be used to enhance the ability of cancer immunotherapies to detect and […]
January 10, 2021

FSU researcher examines ways cocaine alters gene expression

New research from Florida State University identifies a novel gene that plays a functional role in cocaine addiction.   In a new paper in the journal Biological Psychiatry, Assistant Professor of Biological Science Jian Feng and his colleagues reveal that cocaine use in mice resulted in changes to what’s called long noncoding RNA […]
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