November 10, 2020

A more abundant hormone to treat atrial fibrillation

Calcitonin, a well-known thyroid hormone that helps regulate bone mass and collagen production, is also produced by cells in the heart, researchers in Canada, the U.S., the U.K. and Australia have found. Published in Nature, their breakthrough promises to aid in developing new treatments for people with atrial fibrillation (AF), a common […]
November 9, 2020

Diet and lifestyle during pregnancy linked to modifications in infants’ DNA

A new study has shown pregnant women with obesity could reduce the health risks for their infants through improved diet and more physical activity. Research published in the journal PLosMed investigates the impact of high glucose in mothers with gestational diabetes mellitus (GDM) and changes to infants DNA. GDM is […]
November 9, 2020

Researchers show how to target a 'shape-shifting' protein in Alzheimer’s disease

A new study suggests that it is possible to design drugs that can target a type of shape-shifting protein involved in Alzheimer’s disease, which was previously thought to be undruggable. A team of researchers, led by the University of Cambridge, have identified a new mechanism of targeting amyloid-beta, a protein […]
November 9, 2020

Genes that shift butterfly wing colors identified

Cornell researchers have identified three genes responsible for changing the color of common buckeye butterfly wings, depending on what time of year the egg hatches and larvae develop. If the larvae develop early in the year, when days are shorter and colder, the butterflies (Junonia coenia) reach maturity in summer with […]
November 9, 2020

Effective new approach for treating people affected by diabetic eye disease

A new Liverpool led study, published in Diabetologia, presents the results of the largest clinical trial for diabetic retinopathy. The study highlights a new approach that could transform diabetic eye screening around the world that also has a significant cost saving for the NHS. The number of people living with diabetes […]
November 9, 2020

Primordial shapeshifters

It's the holy grail of synthetic biologists: creating a living cell from scratch. So far they’ve managed to make simple prototypes—essentially tiny fat balloons with a soup of genetic material inside, capable of reading genetic code, producing proteins, and transporting molecules around. Yet these artificial blobs lack an essential feature […]
November 9, 2020

MU Researchers Identify how Night-Shift Work Causes Internal Clock Confusion in Body

Night-shift workers face an increased risk of obesity and diabetes, but the underlying reason for that has been a mystery. Now, University of Missouri School of Medicine researchers have found a potential cause for metabolic changes during night-shift work that creates confusion between cells in the body and the central clock in […]
November 8, 2020

Model could improve design of vaccines, immunotherapies

The body's immune system defeats diseases by sensing foreign invaders, such as bacteria or viruses, then mounting a response against them. But how immune cell receptors work together to sense multiple molecules and make these decisions remained a mystery. Now, researchers at the Pritzker School of Molecular Engineering at the University […]
November 7, 2020

Drug Screen in 3-D Cell Culture Identifies Promising Lead Against Bladder Cancer Subtype

Researchers at the University of Michigan Rogel Cancer Center have identified a promising targeted therapy against the basal subtype of bladder cancer by screening 3-D cell cultures. MEK inhibitors showed the strongest response against the basal molecular subtype, the research group reported in Oncotarget. “It’s becoming more and more clear that […]
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