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New King’s College London research reveals how blood inflammation affects the birth and death of brain cells, which could offer new treatment targets for antidepressants. Mounting evidence points to high levels of inflammation as an important biological abnormality leading to depression in at least one third of patients. However, this […]

UCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by David Nathanson, a member of UCLA’s Jonsson Comprehensive Cancer Center, found that the drug combination tested in mice disrupts and exploits glucose intake, essentially cutting off the […]

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood […]

  An international team led by scientists at the National Institutes of Health is the first to discover a new way that cells fix an important and dangerous type of DNA damage known as a DNA-protein crosslink (DPC). The researchers found that a protein named ZATT can eliminate DPCs with […]

You would not expect diamonds to have anything to do with cancer treatment. But they can actually they improve patients’ chances of survival. “Using traditional techniques, it’s almost impossible to determine whether a cancer treatment has been 100 per cent or 99.9 per cent effective. The difference can have major […]

A team of researchers at Cardiff University’s Schools of Pharmacy and Pharmaceutical Sciences, Medicine, and Biosciences, together with the Basque Foundation for Science in Spain, has discovered a new way of tagging these nanobodies that are made naturally by cells. Exosomes play an important role in the way in which […]

Researchers from the Aboobaker lab in the Department of Zoology used the worms (planarians) which are known for their ability to regenerate their tissues and organs repeatedly. This process is enabled by their stem cells, which constantly divide to make new cells. Cell migration – or the movement of cells […]

Proteins and drugs are often attached to lipids to promote crystallization or ensure delivery to targeted tissues within the body, but only the smallest proteins and molecules fit within these fat structures. A new study reveals a lipid structure that can support much larger proteins and molecules than before, potentially […]

UCLA biophysicists have developed a new method to rapidly determine a single cell’s stiffness and size — which could ultimately lead to improved treatments for cancer and other diseases. The method allows researchers to make standardized measurements of single cells, determine each cell’s stiffness and assign it a number, generally […]

New research will seek to understand why people who are HIV positive are more susceptible to a progressive cerebrovascular disease that can ultimately give rise to dementia.  One of the goals of the research is to identify new ways to prevent the blockages that occur in blood vessels and cause […]

The immune system is contantly performing surveillance to detect foreign organisms that might do harm. But pathogens, for their part, have evolved a number of strategies to evade this detection, such as secreting proteins that hinder a host’s ability to mount an immune response. In a new study, a team […]

A new collaboration between two UC Santa Barbara labs explores the underlying molecular mechanism of a remarkable process called anastasis, a Greek word meaning “rising to life.” Building on earlier work showing that cells can recover from the brink of death, the new study demonstrates that anastasis is an active […]