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Substantial numbers of Cleveland’s youngest students have had elevated levels of lead in their blood prior to kindergarten and these children have a higher risk of academic issues, according to two new studies by researchers at Case Western Reserve University. The first study, in coordination with Cuyahoga County’s Invest in […]

Scientists at Washington University School of Medicine in St. Louis have identified a previously unknown route for cellular fuel delivery, a finding that could shed light on the process of aging and the chronic diseases that often accompany it. With age, cells gradually lose their ability to take in and […]

Mice that sleep fitfully could help researchers unravel the mystery of insomnia. Researchers at Washington University School of Medicine in St. Louis studied mice genetically modified to mimic the genetic disease neurofibromatosis type 1 (NF1), which is associated with sleep problems. They found that the animals, like some people with […]

African-Americans may be twice as likely as Caucasian Americans to develop Alzheimer’s disease, but nobody knows why because studies investigating the underlying causes of illness have historically drawn from a nearly all-white pool of research participants. Consequently, little is known about how the neurodegenerative disease arises and progresses in people […]

Longevity is heritable, but that primarily applies to persons from families where multiple members are among the top 10 percent survivors of their birth cohort. The key to a long life can probably be found in the genes of these families. These are the conclusions of researchers at Leiden University […]

Blood levels of a special protein found only in the inner ear spike after exposure to loud noise, UConn Health researchers report. The findings point the way to blood tests that could warn people at risk of hearing loss before they suffer serious damage. Hearing loss can sneak up on […]

A research team from Imperial College London, led by Dr Ben Almquist, has developed a new molecule based on so-called traction force-activated payloads (TrAPs) which allow materials to talk to the body‘s natural repair systems and thereby activate healing processes. “Creatures from sea sponges to humans use cell movement to […]

New clinical trial is evaluating a next-generation approach to replacing damaged knee cartilage with healthy cartilage cultivated from a patient’s own cells. Cartilage, the slippery tissue on the ends of and between bones, provides cushioning and shock absorption. Specifically, in the knee, the articular cartilage at the end of the […]

Researchers at Karolinska Institutet and SciLifeLab have developed a new method of analysis that maps the location of proteins in the cell. The information has been compiled in a database that is accessible to researchers around the world. The method of analysis, which has been published in the journal Molecular Cell, […]

HIPEC, a procedure that combines surgery and heated chemotherapy, gave one patient peace of mind after hundreds of cysts were removed from her abdomen. Melissa Hough considers herself to be patient No. 154. That’s how unusual her condition is. In June, she was diagnosed with cystic mesothelioma. It’s a noncancerous […]

A new study by an international research team including Harvard Medical School faculty has compiled an “atlas” of genetic factors associated with estimated bone mineral density, one of the most clinically relevant factors in diagnosing osteoporosis. The paper, published online in Nature Genetics, identifies 518 genome-wide loci, including 301 newly discovered […]

As genomic sequencing becomes increasingly common in the clinic, questions linger about its use and role in newborn medicine. Can sequencing provide actual actionable insights? How common is it to find something important to a child’s future health? What are the benefits and other consequences of such findings for families? […]